1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP

Brain mechanism linked to relapse after cocaine withdrawal discovered

By Balzafire, Sep 9, 2010 | | |
Rating:
4/5,
  1. Balzafire
    New research has uncovered a specific neural mechanism in the brain that may be linked to persistent drug-seeking behaviour - a find that could aid development of new therapies for cocaine addiction.

    Certain areas in the brain are activated when cocaine users experience a craving for cocaine. The research indicates that increases in the level of brain-derived neurotrophic factor (BDNF) have been observed in these areas in rats after withdrawal from repeated cocaine exposure.

    "It has been shown that increased BDNF in the VTA after cocaine withdrawal in rats promotes the drug-dependent motivational state," said Dr. Mu-ming Poo from the University of California, Berkeley.

    Although a clear correlation between rat and human behaviours of cocaine craving and relapse remains to be established, the cellular mechanism uncovered in this study does appear to have behavioural relevance and may represent a direct brain sensitisation that is involved in triggering relapse.

    The study has been published by Cell Press in the September 9 issue of the journal Neuron. (ANI)


    2010-09-09
    http://sify.com/news/brain-mechanis...awal-discovered-news-scitech-kjjn4heeeic.html

Comments

To make a comment simply sign up and become a member!