Cannabinoid Cancer Fighters the Pharma Industry DONT Want You to Know About

By chillinwill · Sep 18, 2009 · ·
  1. chillinwill
    When the laws surrounding cannabis (an easy to grow 'weed' which any person can grow in their garden with NO technical knowledge or expertise needed) was reclassified a Class B substance in January of 2009 the UK Labour government told the public it was as a result of the 'possible' health risks which could arise from smoking the 'new' strains of cannabis which were super-high in THC.

    A substance which could (might, maybe) cause psychosis in a small number of people who use it regularly.

    And this, regardless of the fact the United States has for over 30 years supplied cannabis to patients who were in receipt of a doctors recommendation.

    Cannabis which is grown on a government funded facility in Michigan no less.

    You couldn't make this up.

    Within the time-scale of cannabis being DE-classified as a class C substance (2004 - the law was changed by THEN Home Secretary David Blunkett), and the recent re-classification back to a class B substance, Canadian medical cannabis advocate Rick Simpson has finally managed to get his story out into the public domain, and quite a story it is too as it tells of a widely available, easy to acquire and perhaps more importantly CHEAP substance which remarkably, has the ability to get rid off blemishes on the skin, including moles and certain types of skin cancer.

    And this, on TOP of its proven analgesic properties, as supported by the American College of Physicians , The Multiple Sclerosis Society and the American Lymphoma and Leukemia Society .

    Hemp Oil
    With direct applications of Simpsons Hemp Oil, which is a heady concoction which comprises of pure THC glands, (this stuff would rock your world if you vaped it in a VaporStar Vaporizer), moles and other cell formations which can rapidly divide and multiply, were seen to just shrivel up and die after a period of exposure.

    Incidentaly, Rick Simpson's evidence has been video-recorded for posterity many times, and you will find an eye-opening collection of his works by visiting Rick Simpson's YouTube movies. Manuel Guzman Study - Madrid
    Then of course we had the cannabinoid study from Madrid , in which Manuel Guzman reported that cannabinoids, the active components of cannabis, inhibit tumor growth in laboratory animals.

    They do so by modulating key cell-signalling pathways, thereby inducing direct growth arrest and death of tumor cells, as well as by inhibiting the growth of blood vessels that supply the tumor.

    All cell division processes have a 'switch'. The reason we have so much trouble curing cancer, is as a result of our inability to find the switch which turns the cancer off. Resulting in cell division gathering pace until it (the cancer) takes over the entire host, (normally a vital organ). At this stage cancer is 'terminal' more often than not.

    Is this a pattern forming? Or just another conspiracy theory?

    Make your mind up only after reading the next section.

    JWH-018 Cures Cancer?
    Published today, September 18th 2009, on a news website dedicated to Urology Professionals, ( ), was the headline; 'Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015' which is a close relation to the newly banned JHW-018.

    And this, after a German scientist claimed to have found a substance romantically named 'JWH-018' in a pouch of Spice artificial cannabis, which would ultimately see Spice being banned from most of the civilised world.

    According to Christopher P Evans M.D, who is a Contributing Editor with UroToday.Com, "..investigators have found that JWH-015 inhibited human prostate cancer cell xenograft growth in mice. The study’s conclusion is that CB2 receptor agonists have potential therapeutic application in the treatment of human prostate cancer.

    So it turns out the active ingredient in Spice artificial cannabis could have cancer curing properties as a result of its ability to 'tweak' our in built CB1 and CB2 receptors. A tweak which is necessary to shut down the processes cancer cells need to multiply and grow.

    So clearly someone in the pharmaceutical industry is playing a big part in keeping nature's safest cure for certain types of cancer, firmly locked away from those that need it most.

    Its quite a story, and one I thought you may be interested in. Please tell your friends.

    By Ian Malley
    CannaZine Cannabis News

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  1. G_nome
    Cannabinoids for treating cancer? View attachment 10786

    Cannabinoids could be useful for treating cancer but cannabis is not. Researchers in Spain have published results in this week's British Journal of Cancer showing that certain cannabinoids – molecules so-called because they were originally found in cannabis – could hold promise for treating prostate cancer.
    So does this mean that smoking cannabis could treat the disease?
    Certainly not. In this paper the researchers were using purified man-made cannabinoids. And they were investigating how to harness the cancer-fighting powers of these chemicals without the mind-bending ones.

    Cannabinoids and cancer
    Certain cannabinoids, such as THC, the main active ingredient in cannabis, have well-documented mind-altering properties. But other cannabinoids have been known for some years to have biological effects elsewhere in the body. Of most interest to cancer researchers is the evidence showing that they can slow the growth and spread of cancer cells, or even kill them.
    For example, Cancer Research UK is funding the work of Professor Chris Paraskeva in Bristol, who is investigating the anti-cancer properties of cannabinoids, as part of his research into the prevention and treatment of bowel cancer.
    It needs to be stressed that these studies have all been done with purified cannabinoid chemicals – not cannabis itself, which contains cannabinoids along with a cocktail of other chemicals. There is no reliable evidence to suggest that smoking cannabis can treat cancer.

    How do they work?
    Cannabinoids affect cells’ behaviour by sticking to receptor molecules on their surface, and triggering a cascade of events within them. There are two main types of cannabinoid receptor, known as CB1 and CB2, although researchers think there may be others out there.
    CB1 is mainly found on nerve cells in the brain – so its likely to be the important one when it comes to the mind-altering effects of cannabis. CB2 is mainly found elsewhere in the body, and is the prime suspect for controlling the other effects of cannabinoids on the body.
    In nerve cells, cannabinoids sticking to CB1 receptors can lead to changes in the signalling pathways (causing the mind-altering and pain-relieving effects of cannabis). We also now know that cannabinoids can trigger other events within the cell, including halting growth or even kick-starting cell death.
    The new research
    In their recent paper, Professor Ines Diaz-Laviada and her team at the University of Alcala in Madrid studied the effects of two cannabinoids – the catchily named Methanandamide (MET) and JWH-015. These are synthetic chemicals that don’t occur naturally in cannabis, although they are similar to compounds found in the plant.
    The researchers tested the chemicals on different human prostate cancer cell lines grown in the lab, and found that they could slow down their growth and trigger cell death. An interesting finding, but which of the two cannabinoid receptors is at work?
    By using drugs that block either one receptor or the other, or a genetic technique called RNA interference to ‘knock out’ CB1 or CB2 in turn, the scientists found that the anti-cancer effects of MET and JWH-015 were brought about by CB2.
    This is an important finding, because it tells us that it should be possible to develop drugs that target CB2, which will have an anti-cancer effect, but which – crucially – won’t have the mind-altering effects of many cannabinoids.
    As a last step, the researchers tested the effects of JWH-015 on mice that had been transplanted with human prostate cancer cells. The chemical helped to slow the growth of tumours, compared with a saltwater control. And blocking the CB2 receptors with a highly-specific drug called SR2 wiped out the effect of JWH-015, proving that it works through the CB2 pathway.

    What does it mean for cancer treatment?
    Although this work is still at an early stage, it provides a tantalising suggestion that drugs that activate the CB2 receptor could be useful for treating prostate cancer. There’s still more research to be done before we know if MET or JWH-015 are suitable for testing in clinical trials involving patients – and no guarantee that these trials would be successful.
    As part of this research, the scientists also investigated the cellular pathways that cannabinoids activate (or block) when they bind to CB2 receptors on prostate cancer cells. By understanding these cellular responses in greater detail, we might discover new targets for cancer treatment.

    So can smoking cannabis treat cancer?
    No. This is a classic fallacy – assuming that because cannabinoids can kill cancer cells in the lab, then cannabis (containing cannabinoids) must be able to treat cancer. Ed has previously written extensively about this, with regard to red wine and cancer.
    This research has been done using man-made chemicals that mimic the compounds found in cannabis, rather than unpurified marijuana. Smoking cannabis, particularly when mixed with tobacco, is likely to increase rather that decrease cancer risk, although the evidence for this is mixed. And, of course, cannabis is classified as an illegal drug in the UK.

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