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Charities warn over rise in demand for killer drug

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4/5,
  1. chillinwill
    DRUGS charities are warning of a rise in demand for a killer drug, nicknamed Special K, in the North.

    Clubbers and addicts are increasingly turning away from ecstasy and heroin to ketamine, a dangerous horse tranquilliser that has been linked to 23 deaths.

    According to a leading drug charity worker, addicts on Teesside are turning to the drug because it’s purer than heroin, while research by Newcastle-based Drugscope found there was an increased use amongst clubbers of the narcotic.

    Tina Williams, of Parents and Addicts Against Narcotics in the Community said: “Ketamine is the new ‘stuff’ and we have a lot of people using. It’s definitely on the increase.

    “It’s a horse sedative and it has a similar effect to heroin. Addicts have cottoned onto this as heroin is now so diluted in the region they can’t even get a hit off it.

    “It’s readily available and now addicts have more options rather than just heroin and crack.

    “Because it’s a class C drug people don’t think that it can be dangerous.”

    Known as Special K, Vitamin K or simply K, the drug is developing a strong following in dance club circuits despite being made illegal three years ago.

    It is usually snorted or swallowed but according to research by Drugscope, more and more people are choosing to inject it.

    At low levels users feel euphoric, experience waves of energy and even a condition called synaesthesia where users’ senses merge into one another.

    But at higher levels the drug can cause paralysis, hallucinations and a disassociation that is close to an out of body experience. It is also a known date rape drug as it has no taste and is odourless.

    In Northumbria Police force area the number of seizures have risen from 96 tablets in 2008 to 144 this year.

    DI Dave Nicholson of Northumbria Police’s drug unit said: “Although there has been a slight rise in grams of Ketamine seized this year, the use of Ketamine is not a significant issue in the force area. I want to reinforce that taking of Ketamine is not safe and can have a devastating impact upon your health.

    “If you become aware of anyone selling or supplying these substances for human consumption, please call police on 03456 043 043 6919. For free advice call the national drug awareness campaign FRANK on 08700 77 6600.”

    The drug claimed 23 lives between 1993 and 2006, mainly through accidents while people are under its influence.

    Phil Doherty
    December 6, 2009
    Sunday Sun
    http://www.sundaysun.co.uk/news/nor...ise-in-demand-for-killer-drug-79310-25330948/

Comments

  1. anarchyat
    SWIM doesn't know where the article got their information about Ketamine, but it is seriously misleading to say the least. For one, Ketamine produces effects no where near like that of herion. They aren't even closely related, as one is an opiate, and the other a dissociative psychedelic. Another gripe SWIM has is that when used properly, Ketamine is a relatively safe and forgiving drug, that is unless used at a higher dosage. Out of body experiences are definately a possibility but could easily be avoided by sticking to a low dose.

    SWIM also finds it amusing that it is always reported that it is a horse tranquilizer, when it is more commonly used in small animal veterinary medicine.

    Also, look at the number of deaths reported, just 23 in 13 years. Compare that to the numerous people who have died on heroin, cocaine, and alcohol!
  2. Spucky
    AW: Charities warn over rise in demand for killer drug

    @ anarchyat:
    [SIZE=-1]PURPOSE: Ketamine is known to interact with opioid receptors. However, because this agent does not produce opioid-like respiratory depression, it might not interact with mu(2) opioid receptors. Therefore, we have studied the interaction of ketamine with mu(2) opioid receptors expressed in SH-SY5Y cells. METHODS: SH-SY5Y cells (passage 70-80) were used to obtain ketamine dose-response curves for inhibition of 0.4 nM [(3)H][D-Ala(2),MePhe(4),Gly(ol)(5)] enkephalin (DAMGO) binding to mu(2) opioid receptors and of forskolin (1 microM)-stimulated cyclic AMP (cAMP) formation. RESULTS: Ketamine displaced [(3)H]DAMGO binding in SH-SY5Y cells with a K(i) of 12.1 microM. However, this concentrations did not inhibit forskolin-stimulated cAMP formation, although at supraclinical concentrations, significant inhibition was observed with an estimated IC(50) of 700 microM.

    C
    ONCLUSION: The present study indicates that a clinically relevant concentration of ketamine interacts with mu(2) opioid receptors.
    However, no agonist activity was observed.

    Source:
    [/SIZE]
    http://www.ketamine.com/opioid-withdrawal.html
  3. anarchyat
    Thanks for that info, SWIM had never read about interaction with the opiate receptors before, although from what he read the main cause of effect is the action on NDMA receptors. SWIM just wanted to point out that experiences on Ketamine and Heroin are markedly different!
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