Company Tables Medical Marijuana for Swine Flu

By chillinwill · Aug 3, 2009 · ·
  1. chillinwill
    Cannabis Science to Move Faster to Release Its Anti-Inflammatory Cannabis

    Cannabis Science Inc. (OTCBB: CBIS), an emerging pharmaceutical cannabis company, is making its anti-inflammatory formulation that targets influenza symptoms one of its top priority drugs to release, as the latest Swine flu numbers are rapidly increasing and have become quite alarming.

    Research indicates that the current H1N1 influenza virus has disturbing similarities to the 1918 pandemic, which killed tens of millions after World War I. Moreover, the young and otherwise healthy population that has been most susceptible to the H1N1 virus is a similar demographic to those most affected in the 1918 outbreak.

    Swine flu, Bird Flu and all influenza strains that elicit excessive inflammatory immune response are targeted with Cannabis Science formulations. The company is developing its strategy for studying the effects of its cannabis lozenge on influenza deaths that are associated with an excessive inflammatory response. A hyper-inflammatory response appears to be the cause of the high mortality (63%) associated with the Avian flu (H5N1), and recent studies indicate a similar risk with the Swine flu (H1N1) as well. The World Health Organization (WHO) released the latest figures and said the virus was "unstoppable" and had become widespread enough to raise the global Swine flu alert to its highest level.

    Dr. Robert Melamede, Ph.D., Cannabis Science Inc. President & CEO, observed, "Contemporary anti-viral medical technology is currently inadequate to meet the World's immediate challenges in dealing with the rapid mutations and infectivity of the numerous influenza viruses. We believe that cannabis extract-based medicines can reduce influenza deaths, and allow infected individuals to develop a strong natural immunity upon recovery."

    Specifically, Cannabis Science Inc. believes that its whole-cannabis extract lozenge will inhibit the development of ARDS (Adult Respiratory Distress Syndrome) associated with deaths from both the Avian and Swine influenza infections. Dr. Melamede believes there is enormous potential value for cannabinoids that naturally prevent excessive inflammatory immune responses. He stated, "Based upon recent discoveries regarding the role that endocannabinoid system plays in maintaining human health, we may have a unique solution to the looming threat posed by deadly influenza strains, which we believe, if implemented, could save millions of lives."

    Previously, Dr. Melamede urged all cannabis consumers, "If you come down with the flu, cease smoking and switch to edibles. We believe that smoking marijuana when a person has influenza will lead to some unnecessary deaths, whereas eating it can prevent unnecessary deaths."

    About Cannabis Science, Inc.

    Cannabis Science, Inc. is at the forefront of medical marijuana research and development. The Company works with world authorities on phytocannabinoid science targeting critical illnesses, and adheres to scientific methodologies to develop, produce, and commercialize phytocannabinoid-based pharmaceutical products. In sum, we are dedicated to the creation of cannabis-based medicines, both with and without psychoactive properties, to treat disease and the symptoms of disease, as well as for general health maintenance.

    This Press Release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Act of 1934. A statement containing works such as "anticipate,"
    "seek," intend," "believe," "plan," "estimate," "expect," "project,"
    "plan," or similar phrases may be deemed "forward-looking statements"
    within the meaning of the Private Securities Litigation Reform Act of 1995.
    Some or all of the events or results anticipated by these forward-looking statements may not occur. Factors that could cause or contribute to such differences include the future U.S. and global economies, the impact of competition, and the Company's reliance on existing regulations regarding the use and development of cannabis-based drugs. Cannabis Science, Inc.
    does not undertake any duty nor does it intend to update the results of these forward-looking statements.

    Cannabis Science Inc.
    Dr. Robert J. Melamede
    July 24, 2009

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  1. Phungushead
    Company Tables Medical Marijuana for Swine Flu

    One Company Hopes a Marijuana Lozenge Will Garner FDA Approval – but Will It Work?

    [IMGL="white"][/IMGL]When most people think of swine flu, they probably don't think of marijuana. But then again, most people aren't Robert Melamede.

    He and his company, Cannabis Science, hope to one day make marijuana available nationwide to kids and teens -- as well as adults -- in the form of a medicinal throat lozenge.

    While medical marijuana has garnered a great deal of attention lately in helping patients deal with chronic pain, Melamede has another application in mind; he believes it can curb death risk from the swine flu.

    The approach relies on the principle that the chemicals in marijuana known as cannabinoids have a dampening effect on the immune system. Melamede said doctors may be able to take advantage of this effect to curb the risk of death from the immune system overdrive that resulted in many of the deaths of young adults during the 1918 influenza pandemic -- a scenario that some worry could occur once more if swine flu were to become more virulent.

    It's a controversial approach -- and few infectious disease experts believe health officials will be quick to approve marijuana prescriptions for sick kids. Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in New York City, is one expert who is troubled by the implications of "giving out THC like water."

    "I don't think many parents would want their kids 'on drugs' for a mild, flu-like illness," he said, "and it's sure to raise hackles with the anti-drug people."

    Still, Cannabis Science, an emerging pharmaceutical cannabis company of which Melamede is president and CEO, is working on an edible form of medicinal marijuana that its officials think will help treat many infectious diseases, swine flu included. Last month, the company announced its intention to apply to the U.S. Food and Drug Administration's fast track approval process in the hope of making its anti-flu lozenge available for a possible second wave of swine flu.

    Melamede said he has already tried the approach himself. In February, when he contracted a nasty flu -- a bout he suspects was related to the H1N1 swine flu virus -- he said he took medicinal marijuana to help his body fight it off.

    Can Cannabis Help Swine Flu Sufferers?

    The concentrated cannabis lozenge was an idea pioneered by Steve Kubby, who, up until two weeks ago, was himself the president and CEO of Cannabis Science. He, too, said he has self-tested his lozenge.

    "Within half an hour of taking it, my runny nose, aching muscles and throat congestion are all significantly relieved," Kubby said, adding that users of the lozenge will not get the "high" or "stoned" effects that come with smoking marijuana.

    Though Kubby and the company parted ways over "financial differences," new CEO Melamede is pushing forward on this idea with even more vigor.

    "Contemporary antiviral medical technology is currently inadequate to meet the world's immediate challenges," Melamede said in a press release issued last week. "We believe that cannabis extract-based medicines can reduce influenza deaths."

    Getting Your Immune System to 'Chill Out'[IMGR="white"][/IMGR]

    The fact that smoking marijuana suppresses your immune system has been known for years, but it wasn't until recently that researchers began to realize that this suppression could be a good thing.

    When you catch the flu, your immune system launches a massive attack on the virus that causes excessive inflammation. This is where the runny nose, sore throat and achiness come from.

    While it is necessary for fighting off the virus, this overwhelming inflammation can start to kill your own cells and, if it gets out of hand, it can lead to organ failure and death.

    When inflammation goes off the handle, the body releases endocannabinoids, which are natural chemicals that suppress the immune system, taking down the inflammation before it does more harm than good. This endocannabinoid system, as it's called, is one of the many systems responsible for maintaining balance and health in the body.

    In more severe strains of the flu, like avian flu, the endocannabinoid system can't always keep up. When this happens, the organs, particularly the lungs, fail.

    "They die not from the virus itself but from their own immune response," Melamede said.

    Curbing Immune Response With Cannabis

    This is where, according to Cannabis Science, marijuana comes in. Because the marijuana plant contains natural, plant-based cannabinoids, called phytocannabinoids, giving cannabis to someone with the flu supplements their body's endocannabinoid system and helps take down the inflammation.

    But could it work for swine flu? Though the current and ex-CEO might not meet eye to eye on many things right now, both feel that the potential for using marijuana for serious strains of the flu, like H1N1, is enormous.

    "It's such a changeable virus that vaccines might not work," Kubby said. "But changing the way our bodies respond to the virus [with cannabis] does work."

    Marijuana for Flu Puts Experts Out of Joint

    While marijuana's anti-inflammatory properties are widely accepted as a treatment for glaucoma or arthritis, its use as an antiviral raises eyebrows even among pot-friendly physicians.

    "Though it may have some antiviral effects, these have not been proven scientifically," says Dr. David Allen, a chest surgeon and cannabinoid research scientist from California.

    Even if suppressing the immune system were the key to fighting off the ravages of swine flu, Horovitz points out, "there are many other immune modulators already on the market that are not derived from illegal substances."

    Dr. Peter Katona, a member of the FDA's advisory committee on new antibiotics, shares the apprehension, saying, "I must be skeptical until there is more data".

    And given that parents, not to mention the federal government's war on drugs, are trying to get kids to "just say no" to marijuana, Melamede's company could face an uphill climb. To get the FDA on board with giving an illicit substance to kids, Cannabis Science will likely be forced to put forth a pretty compelling case for the drug's potential.

    Coming to a Pharmacy Near You?

    Still, since Steve Kubby left the company two weeks ago, Cannabis Science has gone into marketing overdrive, publicizing its "talks" with the FDA and broadcasting the company as a hope for the shaky future of the swine flu pandemic.

    When asked about this publicity, Kubby said he finds it "damaging to the mission" and feels that Cannabis Science is "not playing by the rules."

    Mary Ruwart, who also recently left the company, thinks that Cannabis Science might be putting the cart before the horse. The preliminary studies required to apply for FDA clinical trials take months to complete, she said, and "since these studies were not even on the drawing board when I left three weeks ago, they cannot have been completed."

    Kubby plans to continue his work on the lozenge, which he claimed he has the exclusive rights to.

    "It's a mystery to me how they think they are going to use this technology," he said.

    Melamede maintained that the rights are the property of the company and hence are his to develop. Either way, both men will move forward with the technology in the coming months, but it will be a couple years -- if at all -- before edible products like the cannabis lozenge make it through the FDA's clinical trials.

    Whether marijuana will make the shift from being smoked in the parking lot of the corner drugstore to gracing its shelves remains unknown.

    Kubby noted that the lozenge is a special formulation that acts differently in the body than inhaled marijuana.

    One thing, however, is clear: Smoking marijuana likely will do much more harm than good if you happen to have a respiratory infection -- not to mention that smoking anything is damaging to someone with flu-related respiratory ills.

    As Horovitz put it, "No doctor in his right mind would tell a flu patient to go smoke a joint."

    ABC News Medical Unit
    Aug. 3, 2009
  2. ninjaned
    wow this is a fascinating article, i wonder if people will be able to overcome their drug prejudice in order to accept that big bad cannabis might help save lives.
  3. Nature Boy
    Though I don't think marijuana is ideal for kids, there are far worse medications they could be taking. I'm not talking about puffing back a blunt before kindergarten but a low, controlled dose of cannabis, in butter or whatever, might be beneficial for certain ailments. Not so sure about swine flu but sub-intoxication doses of cannabis have been effective in controlling over-diagnosed and over-medicated conditions like ADHD.

    (Note: Probably shouldn't use the term "intoxicated" when it comes to cannabis seeing as its toxicity is extremely low. It just fit the above sentence better.)
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