Deaths from Tylenol

By enquirewithin · Nov 18, 2005 · ·
  1. enquirewithin
    <h1>Tylenol / Acetaminophen</h1>

    Tylenol is the most popular painkiller in the United States as
    Americans consume over 8 billion Tylenol pills each year. Tylenol or
    acetaminophen is typically used as a pain-reliever (analgesic) and
    fever-reducer (anti-pyretic). Acetaminophen can also be found in many
    over-the-counter and prescription medications such as Nyquil,
    Robitussin, Benadryl, Alka-Seltzer, Vicodin, Percocet, Darvocet, and

    Medical professionals have identified that large doses or long-term use
    of acetaminophens can cause liver damage which may lead to liver
    failure and death. Acetaminophen overdose is the leading cause of liver
    failure in the U.S. and the United Kingdom. The severity of this
    problem has lead to several studies and an educational campaign
    launched by the FDA.

    The American Liver Foundation states that Acetaminophen is normally a
    safe drug but turns into a hepatotoxin when dosed incorrectly or under
    certain conditions. Unfortunately, many people do not take the
    recommended doses or unknowingly take Tylenol in combination with other
    medications or with alcohol. The recommended daily dosage for adults is
    4000 mg but this dosage should be cut in half when using extra-strength
    Tylenol, when consuming alcohol, or when using other drugs containing
    acetaminophen. Parents administering Children’s Tylenol need to be
    especially cautious as recommended child dosages can range from 80-160

    Consumers with a decreased liver function, kidney disease,
    hepatitis, malnutrition, AIDS, chronic ethanol abuse, or anorexia
    nervosa may be at increased risk for liver failure and death when using
    Tylenol. For diabetics, acetaminophen may also affect the results of
    blood glucose (sugar) tests. Some acetaminophen drugs may contain
    aspartame, sulfites or caffeine. While Tylenol has been on the market
    for 50 years, many professionals feel that the proper dosage of
    acetaminophen for children and adults is still unknown and more testing
    and education is necessary to prevent liver damage and accidental

    Acetaminophen is the active ingredient in a variety of
    over-the-counter drugs, most notably Tylenol. Acetaminophen overdose is
    the leading cause of calls to the Poison Control Centers across the
    United States. It is estimated that acetaminophen poisoning calls
    exceed 100,000 per year. Studies indicate that acetaminophen overdose
    results in over 56,000 injuries, 2,500 hospitalizations, and an
    estimated 450 deaths per year.

    The most significant risk involving acetaminophen is acute liver
    toxicity. Data acquired from the U.S. Acute Liver Failure Study Group
    registry indicates that nearly 50% of all acute liver failure in this
    country is linked to acetaminophen poisoning. There have even been
    reported cases of acute liver toxicity in individuals whose
    acetaminophen dosage did not exceed 4 grams/day. Surprisingly, a dosage
    of 4 grams/day falls within the recommended dosage for Extra Strength

    Acetaminophen based drugs have been the cause of acute liver failure in
    hospitals around the country. While the drug can be safe in small
    doses, it can potentially be fatal for those who consume alcohol, take
    the drug in high doses, or simply use it regularly.

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  1. Jatelka
    For those based in the UK: Acetaminophen is Paracetamol, which is often available in combination with codeine (Kapeke, co-codamol etc). SWIM has seen compound preparations used for recreational purposes, and has seen accidental od on paracetamol as a result.

    In certain parts of the world (possibly Australia?)paracetamol is only sold in compound preparations with it's antidote (acetylcysteine). This has no effect on pain relieving effects, but prevents the liver damage (which is caused by toxic metabolites which deplete an enzyme called glutathione).

    Be Safe

    Edited by: jatelka
  2. DoorsPerception
    4000mg seems to be a high daily dose to me
  3. bcStoner420
    Ill say, ill never take anymore than 1500 mg of this stuff in about a 3 day span, and when SWIM uses pills for recreation CWE is always a must. Use the cold water extraction people it could save your liver and possibly your life.
  4. enquirewithin
    What on earth is the recreational value of tylenol?
  5. Muirner
    Ummmmmmmmm nothing, was that a real question? It's just held in the pills such as hydrocodine, darvocet, perkocet. To many pills in one day = BLAH!

  6. bcStoner420
    Ya, like Muirner said, its found in many pharmaceutical opioids/opiates. This is most likely what makes it the leading cause of liver failure, too many neive people popping pills like mad to get messed up not even caring that their loaded with tylenol (or simply not knowing that its so bad for your liver).
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