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  1. Zandorf
    http://www.cnn.com/2005/US/09/30/valium.inventor.ap/index.ht ml





    <b style="font-size: 14px;">TRENTON, New Jersey (AP) -- Leo
    Sternbach, the inventor of a revolutionary new class of tranquilizers
    that included Valium, one of the first blockbuster "lifestyle" drugs,
    has died at his home in North Carolina. He was 97.[/b]


    Sternbach,
    an award-winning chemist who helped the Swiss drug conglomerate Roche
    Group build its U.S. headquarters in Nutley, New Jersey, after fleeing
    the Nazis during World War II, died in Chapel Hill, North Carolina,
    after a short illness late Wednesday.


    His wife, sons and other relatives were at his side, according to the company.


    An
    Austrian native who said he loved chemistry from his youth, Sternbach
    led development of more than a dozen important drugs during a
    six-decade career with Roche.


    His other breakthroughs include
    the sleeping pills Dalmane and Mogadon, Klonopin for epileptic seizures
    and Arfonad for limiting bleeding during brain surgery.


    Valium
    was the country's most prescribed drug from 1969 to 1982. Nicknamed
    "Mother's Little Helper" after the Rolling Stones song, it was three
    times more potent than its predecessor, Librium, another member of the
    class of tranquilizers invented by Sternbach.


    Roche sold nearly 2.3 billion Valium pills stamped with the trademark "V" at the drug's 1978 peak.


    "It
    gave you a feeling of well-being," Sternbach told The Associated Press
    in a 2003 interview on the 40th anniversary of Valium. "Only when the
    sales figures came in, then I realized how important it was."


    Sternbach
    was born in 1908 in Abbazia, part of the Austrian Empire that today is
    Croatia, and earned a doctoral degree in organic chemistry at the
    University of Krakow in Poland. He began working at Roche's Basel
    headquarters in 1940 and in June 1941 fled to the United States with
    his new bride and the rest of Roche's Jewish scientists.


    He and
    his wife, Herta, settled in Montclair, near Roche's U.S. operations,
    called Hoffman-La Roche, raised two sons and lived there until 2003,
    when they moved to North Carolina, where son Daniel works as a chemist
    for GlaxoSmithKline.


    Named one of the 25 most influential
    Americans of the 20th century by U.S. News & World Report,
    Sternbach's credits include 241 patents, 122 publications, honorary
    degrees and other awards.


    As recently as 1994, Roche products for
    which Sternbach held patents brought in more than one-quarter of the
    company's worldwide pharmaceutical revenues.


    Besides his wife and son Daniel, Sternbach is survived by his other son, Michael, and five grandchildren.

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