Invention: Anti-ecstasy antibodies

By dutch-marshal · Mar 30, 2008 · ·
  1. dutch-marshal
    • 13:05 17 March 2008
    • NewScientist.com news service
    • Justin Mullins
    Anti-ecstasy antibodies
    In recent years, crystal meth (methamphetamine) and ecstasy (MDMA) have become some of America's top problem drugs. Meth can cause severe problems in the cardiovascular and central nervous systems. Furthermore, because there is no way to remove the drug from the body, therapies tend to focus on treating its side-effects.

    But antibodies that bind to methamphetamines and methamphetamine-like compounds to effectively remove them from the bloodstream could change that. Michael Owens, director of the Center for Alcohol and Drug Abuse at the University of Arkansas, US, and colleagues claim to have developed a way to generate them.

    The team have not yet tested the antibodies in humans, only in rats, but they say that a single injection can reduce the level of drug within the bloodstream for several days. By binding to drug molecules, the antibodies prevent them from reaching tissues like the heart and brain, and mark the compounds for clean up by the body.
    Owens says that his team's antibodies bind to many drugs from the same chemical "family". Cocaine and nicotine are single, specific compounds but methamphetamines share a basic chemical skeleton with many other drugs. So-called "designer drugs" are made by modifying this skeleton to create specific effects. The team say their therapy works for meth, amphetamines and ecstasy.
    Read the full ecstasy antibody patent application.

    source: http://technology.newscientist.com/...tasy-antibodies.html?feedId=online-news_rss20



    more info: http://www.wipo.int/patentscopedb/e...87602&IA=US2007071354&LANG=ENG&DISPLAY=STATUS

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Comments

  1. stoneinfocus
    great, looks like a new torture drug and as much fun as lobothomizing "atypical" anti-psychotics, espacially the statement "binds to drugs of the same family".
    Anybody dreaming of shooting inventors, media and activists and maybe their familymembers and friends.. then it would be even, for both sides.
  2. psyche
    How about endogenous phenetylamines or those contained in food? Are they going to be victims of this 'anti-ecstasy' drug too? On the other hand this is a very good finding that can save many, many people's life, yes, but unfortunately it has been developed for all the wrong reasons: to irradicate the freedom of choice from people.

    Edit: On a closer look at the patent site, it seems to recognize (+) amphetamine, (+) methamphetamine and (+) 3,4 methylenedioxymethamphetamine, but not the (-) stereoisomers(?). Is that really true? Does it still mean that many of the natural phenethylamines are going to get victimized by this antibody?
  3. stoneinfocus
    yes, may drugs cost some few lifes, depending on many influencial circumstances as does driving, and hobbies and work do.

    Drugs don´t cost the incancerated fear-loaded, hunted, prosecuted miserable being of humans as do laws and forced treatments do big time!Personal Freedom and autonomity of his own life is worth taking the risks of any chosen consequences one does to himself!
  4. RaverHippie
    this has been posted already
  5. stoneinfocus
    Yep... but nice to discuss again the probable consequences ... maybe good as an emergency drug, but themere thought of using it as an forced treatment to cut down personal choices is unethical and dictative.
  6. Expat98
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