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  1. Beenthere2Hippie
    Throughout the bodies of every human on the planet is a physiological system that plays a crucial role in establishing and maintaining human health. The endogenous cannabinoid system (ECS), discovered by scientists unafraid of studying marijuana, is made of endocannabinoids and their receptors which are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells.

    The goal of the ECS is to maintain homeostasis within your body.

    While the human body produces its own version of endocannabinoids to stimulate these receptors, scientists have discovered that phytocannabinoids, plant-based substances, can also stimulate these cannabinoid receptors. The most well-known, and most psychoactive phytocannabinoid is Delta-9-tetrahydrocannabinol, or THC, which is derived from the cannabis plant. However, other, non-psychoactive cannabinoids such as cannabidiol (CBD) and cannabinol (CBN) are gaining the interest of researchers due to a variety of healing properties.

    There are over 20,000 articles searchable on PubMed detailing the effects of “cannabinoid”(s). New research has shown that cannabis is an effective treatment for a myriad of ailments ranging from cancer, to epilepsy, to PTSD.

    These seemingly miraculous benefits have gotten the attention of the pharmaceutical industry which is likely interested in profiting from said benefits. The thing about cannabis, however, is that it doesn’t need Big Pharma to produce it, package it and distribute, as it can grow in your backyard.

    But, when government-connected industries wish to shut out their competition, which in this case is a plant, they lean on the state’s ability to stifle competition through claiming a right to the intellectual property behind a particular set of ingredients – otherwise known as a patent.

    Since no one can patent a wild plant, pharmaceutical industries turn to their labs and chemistry to recreate nature. The drug Marinol is an example of a pharmaceutical chemical compound that is produced by Solvay Pharmaceuticals Inc. and used to mimic nature. It contains a nearly identical molecular structure as the THC molecule and has similar effects of marijuana on cancer patients in regards to increasing appetite, etc. But unlike its natural counterpart, Marinol does not grow on trees.

    This impulse to exclusively own the rights to life-saving medicines is nothing new. However, with the ever-increasing scientific data showing the miraculous effects of cannabis on healing the human body, Big Pharma is hurriedly attempting to imitate these same effects — in their labs. This haste is proving to be deadly, at least in one example, in France.

    According to Ouest France, a recent test conducted by Biotrial, on behalf of the Portuguese pharmaceutical company Bial, has left six people hospitalized in Rennes. One of those six people was declared clinically dead at the University Hospital of Rennes last week. After news of the hospitalizations broke, media around the world began putting out misleading headlines about cannabis research being the cause. However, according to Marisol Touraine, France’s Minister of Health, cannabis was not involved in these studies at all, only a synthetic ECS stimulant designed to mimic cannabis’s effects.

    The effects of the synthetic chemical compounds on the endocannabinoid system were, indeed, a dangerous factor. The pill acted on the body’s endocannabinoid system. Taken orally, the drug was undergoing a Phase 1 clinical trial at a licensed private European laboratory that specializes in clinical trials, the French health ministry said. Attempting to recreate the natural analgesic effects of cannabis, this pharmaceutical company unwittingly killed someone and gravely injured several others.

    Why would these serious risks be taken when cannabis provides a clearly safer alternative?

    Well, for starters, in countries around the planet, in order to study the effects of cannabis, it is particularly difficult — because it is illegal. Big pharma also plays a large role in why cannabis is illegal too, as they lobby state officials to keep it that way. However, the crumbling illegality of cannabis is only part of the reason Big Pharma is rushing into the lab to synthesize its effects. As the Free Thought Project pointed out earlier this month, a new survey of adults found that 80% of respondents reported substituting cannabis for their prescription drugs. There is a mass exodus from pills to pot — and the industry is scared.

    Of course, no one is advocating for the cessation of pharmaceutical innovation as many pharmaceutical medications have proven to be incredibly beneficial. However, when governments and Big Pharma collude, through the use of patents and prohibition, to create a synthetic product, that merely mimics the effects of a plant ingested by millions daily, and people are hurt in the process, something must be said. Matt Agorist is an honorably discharged veteran of the USMC and former intelligence operator directly tasked by the NSA.

    This prior experience gives him unique insight into the world of government corruption and the American police state. Agorist has been an independent journalist for over a decade and has been featured on mainstream networks around the world.

    By Matt Agorist - The Free Thought Project/Jan. 19, 2016
    Photo: International Business News
    Newshawk Crew

    Author Bio

    BT2H is a retired news editor and writer from the NYC area who, for health reasons, retired to a southern US state early, and where BT2H continues to write and to post drug-related news to DF.


  1. Phenoxide
    Re: Is Big Pharma's Push to Develop Cannabinoid Drugs Killing Its Human Test Subjects

    Stopped reading after this. Marinol is THC. If the author wants to write yet another 'plants good, pharmaceuticals evil' rant, then they could at least get the very basic facts straight.
  2. Gradois
    Re: Is Big Pharma's Push to Develop Cannabinoid Drugs Killing Its Human Test Subjects

    Yes, Marinol is THC. It's even Δ9-tetrahydrocannabinol, the same as the THC from cannabis. But Marinol and the THC from cannabis are differnt isomers of Δ9-tetrahydrocannabinol (isomer -> same chemical formula, but the atoms are structured differently) so they're not exactly the same molecule.

    eidt: But yeah, I don't think a pure THC-extract from cannabis is any better/worse than Marinol. And although there are a lot of 'plants good, pharmaceuticals evil'-rant here, the article isn't making that claim about Marinol.
  3. Phenoxide
    Re: Is Big Pharma's Push to Develop Cannabinoid Drugs Killing Its Human Test Subjects

    I don't believe that's the case. The predominant active (>95%) in Marinol is the levorotary trans isomer of THC, which is also the predominant stereoisomer in the cannabis plant.
  4. detoxin momma
    Re: Is Big Pharma's Push to Develop Cannabinoid Drugs Killing Its Human Test Subjects

    i myself have tried marinol a few times.

    i didnt notice any feeling different from smoking the plant itself.
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