1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP
  1. chillinwill
    Drug treatment options for depression can take weeks for the beneficial effects to emerge, which is clearly inadequate for those at immediate risk of suicide. However, intravenous (IV) ketamine, a drug previously used as an anesthetic, has shown rapid antidepressant effects in early trials.

    Researchers have now explored ketamine’s effects on suicidality in patients with treatment-resistant depression, and are publishing their results in the Sept. 1 issue of Biological Psychiatry. Ketamine acutely reduced suicidal thoughts when patients were assessed 24 hours after a single infusion. This reduction in suicidality was maintained when patients received repeated doses over the next two weeks.

    Corresponding author Rebecca Price commented on these encouraging findings: “If these findings hold up in larger samples of high-risk suicidal patients, IV ketamine could prove an attractive treatment option in situations where waiting for a conventional antidepressant treatment to take effect might endanger the patient's life.”

    Since this was a preliminary study in a small group of depressed patients, further research is needed to replicate these results. However, the findings are promising and could result in improved treatment for suicidal patients in the future.

    Journal reference:

    • Rebecca B. Price, Matthew K. Nock, Dennis S. Charney, and Sanjay J. Mathew. Effects of Intravenous Ketamine on Explicit and Implicit Measures of Suicidality in Treatment-Resistant Depression. Biological Psychiatry, 2009; 66 (5): 522 DOI: 10.1016/j.biopsych.2009.04.029
    September 13, 2009
    ScienceDaily
    http://www.sciencedaily.com/releases/2009/09/090910084151.htm

Comments

  1. Alfa
    It would be interesting to see if these results will be consistent with a study with 200+ patients. The current study used 26 patients.
  2. Jatelka
To make a comment simply sign up and become a member!