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  1. Balzafire
    Pharmacists and chemists have found another use for the multipurpose cannabis as a source of antibacterial chemicals for multidrug resistant bacteria. Ironically, inhaling cannabis is known to damage the lung's ability to fend off invading pathogens, but the ingredients in cannabis, particularly the cannabinoids, have antiseptic properties. Although scattered research has been conducted since the 1950s, no comprehensive study existed that relates the structure of cannabinoids with antibacterial activity. Giovanni Appendino, Simon Gibbons, and coworkers attempted to remedy that problem by examining the activity of five common cannabinoids and their synthetic derivatives.

    All five cannabinoids (THC, CBD, CBG, CBC, and CBN) were potent against bacteria. Notably, they performed well against bacteria that were known to be multidrug resistant, like the strains of MRSA that plagued U.K. hospitals. CBD and CBG have the most potential for consumer use because they are nonpsychotropic.

    Besides identifying antibacterial capability, the researchers wanted to figure out why these cannabinoids are so good at killing bacteria. They obviously are very effective at specifically targeting some vital process in the bacteria. Unfortunately, even after extensive work at modifying the cannabinoids and comparing their activities, that targeting mechanism remains a mystery. The scientists were able to figure out that the position of the n-pentyl chain (orange) relative to the terpenoid moiety (blue) serves to control lipid affinity.

    These cannabinoids are promising enough to warrant rigorous clinical trials. They are applicable as topical antiseptics, biodegradable antibacterial compounds for cosmetics, and systematic antibacterial agents.


    By Yun Xie
    August 26, 2008
    http://arstechnica.com/science/news/2008/08/killing-bacteria-with-cannabis.ars

Comments

  1. Terrapinzflyer
  2. Balzafire
    ^^^^ This is not the first time you have done this.
    Posting links to related articles like this is an amazingly valuable contribution to an educational thread and makes it easy for readers to access additional information.
    Thanks. This is the kind of cooperative teamwork that makes Drugs-Forum a world class source for news and unbiased information on recreational drugs.
    I went ahead and linked all 4 articles with appropriate tags as well.
  3. xenos
    The pet robot and company are very regular cannabis smokers(at least 5 bowls a day). They noticed that during times that they did not have any cannabis, they would be more prone to getting sick. Besides those times that they didn't have any cannabis, the pet robot has rarely if ever gotten sick during the past 6 years of habitual cannabis smoking. Could this be related to these findings?
  4. Balzafire
    ^^^ It's entirely possible Xenos, as more is being learned every day about the benefits of cannabis consumption. I would be interested in other peoples views on that, too.
    Back in the day when my deviant cousin smoked cannabis in large amounts on a daily basis however, he did tend to have a nasty cough most of the time. He attributes that to inflammation of his bronchi from smoking so often. He was a frequent tobacco smoker as well though, so he's sure the combination of both contributed to his distress.
    His son is now a heavy cannabis smoker who also smokes tobacco and he sees similar coughing from him. He calls it a "morning cough" to "clear his lungs". My cousin calls bullshit, preferring to refer to it as "marijuana bronchitis".
  5. C.D.rose
    Personally, I don't believe that it'd work that way. I think that in the absence of cannabis, the robot's system was sort of thrown off the tracks, and that made him more vulnerable to infections. Unless the antibacterial effects of cannabis have a totally revolutionary mode of action, the bacteria in one's body would get "resistant" to its effects with chronic exposure, wouldn't they?
  6. venkecske
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