1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP

Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetration

By Alfa, Apr 8, 2009 | | |
  1. Alfa
    Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetration

    Men with premature ejaculation who used a topical spray five minutes before intercourse were able to delay their orgasm six times longer than normal, according to a study in the April issue of BJU International.

    Three hundred men with clinically diagnosed lifelong premature ejaculation (PE) from 31 centres in the UK, Czech Republic, Hungary and Poland, were randomised into two groups. Two hundred used the PSD502 spray, which contains 7.5mg of lidocaine and 2.5mg of prilocaine, and 100 used a placebo spray with no active ingredients.

    Every time they had intercourse during the three-month study period, each couple measured the time from vaginal penetration to ejaculation with a stopwatch. The men were asked to abstain from sexual activity or masturbation for 24 hours before each recorded encounter.

    The time from penetration to ejaculation increased from an average of 0.6 minutes to 3.8 minutes in the medicated group and to just 1.1 minutes in the placebo group.

    When these figures were adjusted to take account of any variations between the two groups, these showed that the treatment group were able to last 6.3 times longer after penetration when they used the spray. The placebo group lasted 1.7 times longer.

    “Premature ejaculation can be a very distressing condition for men and can cause distress, frustration and make them avoid sexual intimacy” says lead researcher Professor W Wallace Dinsmore from the Royal Victoria Hospital, Belfast, UK.

    The research team used the evidence-based definition of lifelong PE developed by the International Society for Sexual Medicine to select their study subjects. This states that ejaculation occurs within about one minute of vaginal penetration in the majority of encounters.

    “Because this definition was only launched in 2008, studies have yet to determine the prevalence of lifelong PE in the male population” says Professor Dinsmore. “But previous research suggests that as many as 40% of men will experience premature ejaculation at some time in their lives.”

    The 300 men who took part in the phase three, multicentre, double-blind, randomised study had an average age of 35. The majority had used other treatments before, the most common being oral antidepressants.

    After three months of treatment the researchers reported that:

    * 90% of the men in the treatment group were able to delay ejaculation for more than one minute following vaginal penetration, compared with 54% in the placebo group.
    * 74% of men in the treatment group managed to last more than two minutes before ejaculation, compared with 22% in the placebo group.
    * 62% of men in the treatment group said their orgasms were ‘good’ or ‘very good’ after three months, compared with 20% before the study started. The figures for the placebo group were slightly lower at the end (19%) than at the start (21%).
    * 66% of men in the treatment group said the medication was ‘good’ or ‘excellent’ compared with 15% in the placebo group.
    * A significantly higher percentage of the patients and partners in the treatment group reported improvements when it came to perceived control, personal distress, satisfaction with sexual intercourse and interpersonal difficulties.
    * There were no serious adverse events reported during the study. Adverse treatment-related reactions were reported by five men and six women from the treatment group and one man from the placebo group. The most common problems were loss of erection and a burning sensation in the vagina.

    “Our study shows that when the PSD502 spray was applied to the man’s penis five minutes before intercourse it improved both sexual performance and sexual satisfaction, which are key factors in treating premature ejaculation” says Professor Dinsmore.

    “It was well tolerated by both patients and their partners, with no systemic side effects and a low incidence of localised effects and was rated favourably by the majority of users.

    “We believe that this shows that PSD502 offers significant advantages over other therapies being developed for the treatment of premature ejaculation.”

    Journal reference:

    1. Dinsmore et al. PSD502 improves ejaculatory latency, control and sexual satisfaction when applied topically 5 min before intercourse in men with premature ejaculation: results of a phase III, multicentre, double-blind, placebo-controlled study. BJU International, 2009; 103 (7): 940 DOI: 10.1111/j.1464-410X.2009.08456.x

Comments

  1. beentheredonethatagain
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio

    Geez those poor women, they must be fustrated as hell , two pumps and a squirt and their men are done , smoking the cigarette.

    I can't remember having this problem , although cumming after a short session can happen if its been a whille , as you know , that stuff can build up and once it does, LOOKOUT! :eek:
  2. honourableone
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio

    This is an amazingly simple solution that just uses local anaesthetics. It's odd that this hasn't been tried sooner, although it's far from a perfect solution if the average was still 3.8 minutes. Guys that last less than o.6 minutes must feel like complete shit, so I suppose this is still a step in the right direction. This stuff could be put into condoms easily.
  3. beentheredonethatagain
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio

    putting this onto condoms may not work, it could cause them to leak ?

    I thought that those local anaesthetics had to go under the skin , to get the numbing effect?
  4. honourableone
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio

    Putting spremicides into condoms seems to be fine, although I suppose that could be a special case given their purpose...

    Some anaesthetics work topically, and I can only assume that this would be more effective when applied to more delicate tissues, which is why the local anaesthetics seem to work so well here, and in oral throat lozenges.
  5. beentheredonethatagain
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio

    the guys who now last 3.8 minutes must feel like they've pulled an all nighter.

    reminds me of a Stones' tune Let It Bleed
    " well we all need someone we can cream on "
  6. Kelveren
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio

    There's already something like this in some Trojan condom or other. Had a few friends actually complain about it as none of them were premies.
  7. yaba
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio

    This has been freely available in Amsterdam (10 years ago) named stud spray basically lidocaine in a spray.
  8. blipblop
    Re: Premature Ejaculation Spray Enables Men To Last Six Times Longer After Penetratio


    Urgh, poor women indeed:p
    All I could think of during that article was "wait, what, multiple women agreed to go back for more 40-second sex sessions?! THREE HUNDRED women agreed to it?"
    I mean kudos to them, donate a few seconds to science, but I sure as hell wouldn't go back for more.
To make a comment simply sign up and become a member!