1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP

Saliva Test to Diagnose GHB and Alcohol Poisoning Developed by UK Scientists

By Beenthere2Hippie, Jan 8, 2016 | |
  1. Beenthere2Hippie
    Scientists working at Loughborough University, UK, and the University of Cordoba, Spain, have developed a new method for the rapid diagnosis of poisoning in apparently drunk patients.

    The saliva-based test offers the potential to screen for poisons commonly associated with the cheap or imitation manufacture of alcohol, and γ-hydroxybutyric acid, the so-called 'date rape' drug GHB.

    The results are published today, Jan. 8, 2016, in the Journal of Breath Research.

    "Many people attending accident and emergency departments have some kind of alcohol-related issue, particularly at the weekends," explains Paul Thomas, Professor of Analytical Science at Loughborough University, and co-author of the paper. "We're aiming to develop a test that is as simple as taking temperature with a thermometer that detects when patients are more than just drunk."

    The researchers developed a test which detects the presence of methanol, ethanol, ethylene glycol, propan 1,3 glycol and γ-hydroxybutyric acid.

    These chemicals were added to 'fresh' saliva collected from three healthy volunteers.

    "It was particularly challenging stabilising concentrations low enough to be realistic simulations of what you'd expect to find clinically," adds Thomas. "But we've managed to make some sensitive measurements -- which is quite pleasing as saliva is a particularly complicated material to work with due to the presence of bacteria and their metabolites from the mouth, and ammonia at high enough levels to change the chemistry of the measurement system unless carefully managed."

    Once the chemicals were added to the fresh saliva the researchers used an oral sampler to extract methanol, ethanol, ethylene glycol, 1,3-propandiol and γ-hydroxybutyric acid. The compounds were detected using gas chromatography-differential mobility spectrometry.

    "We were surprised at the ease at which we could detect γ-hydroxybutyric acid," continues Thomas. "It's both a polar and acidic molecule - but it turned out to be easy to detect, even at the low concentrations we were studying."

    The researchers are now working on running trials of their test in a clinical setting, on patients in emergency departments.

    "We're hoping to demonstrate that this test will be simple, effective and useful for clinicians to use," concludes Thomas. "I think this is a very exciting area of research and in the next few years there will be a host of simple tests on breath, skin and saliva that will aid with diagnosis in hospitals."




    Eureka org/Jan. 7, 20`6
    http://www.eurekalert.org/pub_releases/2016-01/iop-stt010616.php
    Newshawk Crew

    Author Bio

    Beenthere2Hippie
    BT2H is a retired news editor and writer from the NYC area who, for health reasons, retired to a southern US state early, and where BT2H continues to write and to post drug-related news to DF.

Comments

To make a comment simply sign up and become a member!