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Top Ten Most Dangerous Drugs

  1. Vater Satan mit uns
    What does it mean for a drug to be “dangerous”? Though there are many well-respected methods of determining dangerous drugs, this list was compiled using a study published in Scientific Reports this year. The study used a measurement called the margin of exposure, or MOE, to determine which drugs were the most dangerous.

    A drug’s MOE is determined by calculating the ratio of toxicological threshold (the amount of drug you have to take to experience a physiological effect) to estimated human intake. The lower the ratio, the more dangerous the drug. Below, we present the top 10 most dangerous drugs according to their MOE.

    Number Ten: Cannabis. Least dangerous on this list is cannabis, or marijuana. This is because it would take an immense amount of marijuana to actually kill a person. Though marijuana is widely used and is known to impair its users, the chances of someone taking a lethal dose of marijuana are extraordinarily low.

    Number Nine: Diazepam. Better known as Valium, Diazepam is a benzodiazepine commonly prescribed for anxiety, seizures and muscle spasms. It is highly addictive and, in high enough doses, will kill you.

    Number Eight: Amphetamine. Amphetamine is a stimulant that controls your central nervous system. It has become widely popular as a salt in the form of Adderall, which is commonly prescribed for ADHD and is used recreationally by many high school and college students.

    Number Seven: Methadone. Methadone is most commonly administered to recovering heroin addicts who are suffering from withdrawal. Though it is not commonly viewed as dangerous, for non-heroin addicts, it can be lethal.

    Number Six: Meth. Meth, or methamphetamine, is a highly addictive stimulant that is similar, but more addictive than, amphetamine. It was highly popularized by AMC’s Breaking Bad (pictured above).

    Number Five: MDMA. MDMA, also known as Molly, is the pure form of the active ingredient in ecstasy. It has both stimulant and hallucinogenic properties and has become popular for young people to use before going to concerts or raves.

    Number Four: Nicotine. Nicotine is one of the most decriminalized drugs on this list, but it’s also one of the most dangerous. It is a mild stimulant, but its danger lies in its delivery; the most common way to ingest nicotine is by smoking it. Even though e-cigarettes have recently grown in popularity, it is still extremely dangerous, and it only takes one cigarette to become addicted.

    Number Three: Cocaine. Cocaine is a stimulant that is extremely addictive and powerful. It is made from the coca plant, which is native to South America. Though cocaine use does result in short-term euphoria and increased sociability, it can also raise heart rate and blood pressure to dangerous levels.

    Number Two: Heroin. Many people consider heroin the most dangerous drug, but that’s where they’d be wrong. However, it’s true that heroin is extremely dangerous. Also known as smack or H, heroin is an opioid that is synthesized from morphine. An estimated 23 percent of people who have ever used heroin become addicted to it.

    Number One: Alcohol. Yes, it’s true: the most dangerous drug available to us is alcohol. Though alcohol is extremely popular, decriminalized and in some instances even romanticized, it is addictive, harmful and lethal in many cases. Many people who are unaware of their limits accidentally poison themselves with alcohol and can even die from an accidental overdose. For this reason, alcohol is the most dangerous drug.

    Source: PPcorn


  1. Diverboone
    Very interesting. Could you cite the actual article/study? Not that I'm in doubt but rather be able to reference a source if I choice to use this information in future post/debates.
  2. trdofbeingtrd
    Most dangerous even by MOE and yet datura and inhalants are nowhere on the list. Glad they put alcohol on there, just interesting that these lists of top 10's always have cannabis but yet leave out drugs people do that are catastrophic regarding being dangerous.
  3. profesor
    (Meth) was highly popularized by AMC’s Breaking Bad." This is worded badly. It sounds like the author is blaming the epidemic on a TV show. "Publicized" would be better than "popularized".
    Marijuana should not be in the top ten. Glue and other huffing agents are very dangerous, should be on there
    What the hell is this source "PPcorn", anyways? A website? It sounds terrible.
  4. Name goes here
    That article is a load of horse shit. I'm seeing a ton of problems but a couple stand out:

    "and it only takes one cigarette to become addicted." Really? Does anyone believe that?

    "Nine: Diazepam" grand mal seizures anyone? Long term brain changes. While short term use is fairly safe, long term has loads of problems.
  5. Vater Satan mit uns
    It would not let me link the site. Some message came up.
  6. Vater Satan mit uns
    I agree with you. The reason why I posted it is to get insights and opinions on it. The order they are in too does not really make too much sense either. Marijuana should not even be considered dangerous.

    With cigarettes, I am inclined somewhat to agree with. I was hooked after my first one.

    Diazepam probably dimmed my memory to an extent, but all the meds I take now have taken a toll on it. Lately, I have been forgetting names of people and such.
  7. Diverboone
    The OP is having an issue posting links. So on their behalf I'll upload the published research article.
    View attachment 47455
  8. trdofbeingtrd
    I was addicted to nicotine after my first ciggerette butttt
    It's true that not everyone is.

    Diazepam is not dangerous when taken medically as prescribed IF the doctor prescribing did their homework first.
  9. Diverboone
    I and I'm sure other members may have taken this survey or remember when it was taken. This is how the drug user ranked the benefits and harms of recreational drugs.

    There have been several recent efforts in the UK and the Netherlands to describe the harms of psychoactive substances based on ratings of either experts or drug users. This study aimed to assess the perceived benefits as well as harms of widely used recreational drugs, both licit and illicit, in an international sample of drug users. The survey was hosted at https://www.internationaldrugsurvey.org/ and was available in three languages. Residents reported their experience of 15 commonly used drugs or drug classes; regular users then rated their harms and benefits. In all, 5791 individuals from over 40 countries completed the survey, although the majority were from English speaking countries. Rankings of drugs differed across 10 categories of perceived benefits. Skunk and herbal cannabis were ranked consistently beneficial, whilst alcohol and tobacco fell below many classified drugs. There was no correlation at all between users’ harm ranking of drugs and their classification in schedules of the USA or ABC system in the UK. Prescription analgesics, alcohol and tobacco were ranked within the top 10 most harmful drugs. These findings suggest that neither the UK nor US classification systems act to inform users of the harms of psychoactive substances. It is hoped the results might inform health professionals and educators of what are considered to be both the harms and benefits of psychoactive substances to young people.
    Morgan CJ, Noronha LA, Muetzelfeldt M, Fielding A, Curran HV. Harms and benefits associated with psychoactive drugs: findings of an international survey of active drug users. Journal of Psychopharmacology (Oxford, England). 2013;27(6):497-506. doi:10.1177/0269881113477744.

    View attachment 47456
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