Hello all, this is a weird question that may or may not require basic pharmacology to explain. Some time ago, SWIM
first started experimenting with opiates
. SWIM started on some low doses [5 or 10mg at a time] which were spaced out between about a week between each other and at least a week prior to a high dose, about 3 low-dose experiences total...
For a higher dose SWIM took--with no tolerance and on empty stomach
--5 x [5mg prescription oxycodones--"percocet"]--25mg total
--(SWIM did this via a cold water extraction to remove the APAP
and drank the opiate
water)... it was a great experience, felt fine afterwards.
Just recently, SWIM found some again, though a little different... this time SWIM took 1 x 5mg pill about 5 days before a high dose experience. SWIM then took 3 x [5mg prescription instant release
--again with no tolerance and on empty stomach
SWIM did this normally by swallowing them whole after reading that roxis contained no APAP. However, this time, something went wrong. SWIM got sick... SWIM felt really drowsy, got the itching sensations and mild euphoria
but not even the amount of euphoria SWIM got with just one roxi 5 days before, and had a sick feeling in SWIM's head (nausea, only not a stomach-pain type of nausea, this was a headache-nausea). SWIM vomitted about 4 times that night.
Here is the catch
, which may or may not be responsible. A day before the bad time with 3 roxicodones, SWIM had been using cleaning chemicals (namely bleach
and mr. clean
) to clean a floor in an enclosed area, and SWIM got a headache and swollen throat glands afterwards so SWIM thinks he had mild chemical poisoning (but no fainting or nausea). SWIM immediately began taking immune supplements for that day and the next like NAC, pure vitamin C powder, vitamin D, etc. but still, felt kinda sick (although less than before) the next day when SWIM took the roxis.
1) Do you think the chemical poisoning preoccupied SWIM's immune system such that it lead SWIM's body to reject any further intoxicatants (roxicodone)?
2) If #1 is no, then why did this not
happen with 25mg the first time, but with the second time when SWIM took even less-- 15mg total. Could it be due to the instant release factor of the roxis? (Although wouldn't a cold water extraction make the [percs SWIM took the first time] instant release?
3) Could it be because SWIM developed tolerance the first time (although they werent too close together in time) that SWIM did not get sick? If one were taking 5 or 10mg oxycodone
on 4 occasions, how close would those occasions have to be in time to create tolerance?
Please give SWIM any insight you can contribute, as SWIM would like to try roxis again but do not want the same horrible experience... help is much appreciated.