is going to try using Zantac the next time it and amphetamine
Also found this list of different drug
interactions with amphetamine:
Note that this list includes potentiators and things that diminish effects.
-Gastrointestinal acidifying agents (guanethidine, reserpine, glutamic acid HCl, ascorbic acid, fruit juices, etc.) lower absorption of amphetamines
Urinary acidifying agent
-(ammonium chloride, sodium acid phosphate, etc.) increase the concentration of the ionized species of the amphetamine molecule, thereby increasing urinary excretion. Both groups of agents lower blood levels and efficacy of amphetamines.
-Adrenergic blockers are inhibited by amphetamines.
-Gastrointestinal alkalinizing agents (sodium bicarbonate, etc.) increase absorption of amphetamines. Co-administration of ADDERALL
® and gastrointestinal alkalizing agents, such as antacids, should be avoided. Urinary alkalinizing agents (acetazolamide, some thiazides) increase the concentration of the non-ionized species of the amphetamine molecule, thereby decreasing urinary excretion. Both groups of agents increase blood levels and therefore potentiate the actions of amphetamines.
-Amphetamines may enhance the activity of tricyclic or sympathomimetic agents; d-amphetamine with desipramine
or protriptyline and possibly other tricyclics cause striking and sustained increases in the concentration of d-amphetamine in the brain; cardiovascular effects can be potentiated.
antidepressants, as well as a metabolite of furazolidone, slow amphetamine metabolism. This slowing potentiates amphetamines, increasing their effect on the release of norepinephrine and other monoamines
from adrenergic nerve endings; this can cause headaches and other signs of hypertensive crisis. A variety of neurological toxic effects and malignant hyperpyrexia can occur, sometimes with fatal results.
-Amphetamines may counteract the sedative effect of antihistamines.
-Amphetamines may antagonize the hypotensive effects of antihypertensives.
-Chlorpromazine blocks dopamine
and norepinephrine receptors, thus inhibiting the central stimulant
effects of amphetamines, and can be used to treat amphetamine poisoning.
-Amphetamines may delay intestinal absorption of ethosuximide.
-Haloperidol blocks dopamine receptors, thus inhibiting the central stimulant effects of amphetamines.
-The anorectic and stimulatory effects of amphetamines may be inhibited by lithium carbonate.
-Amphetamines potentiate the analgesic effect of meperidine.
-Urinary excretion of amphetamines is increased, and efficacy is reduced, by acidifying agents used in methenamine therapy.
-Amphetamines enhance the adrenergic effect of norepinephrine.
-Amphetamines may delay intestinal absorption of phenobarbital; co-administration of phenobarbital may produce a synergistic anticonvulsant action.
-Amphetamines may delay intestinal absorption of phenytoin; co-administration of phenytoin may produce a synergistic anticonvulsant action.
-In cases of propoxyphene overdosage, amphetamine CNS stimulation is potentiated and fatal convulsions can occur.
-Amphetamines inhibit the hypotensive effect of veratrum alkaloids.
This is from professional PDR located at http://www.rxlist.com/adderall-drug.htm
Now this doesn't really go into the pharmacology of why the different substances potentiate or reduce the effectiveness of amphetamine but it lists a lot of different interactions that could happen.