Grapefruit juice (and other juices) are known to effect the absorption of drugs
, by interfering with the enzymes that break down substances in the stomach. Sometimes more of the drug
will get into the system as a result. Other juices such as apple have a similar effect, but bear in mind that juices can do the opposite with some drugs, reducing the effects of a given dose!
Doctors advise not to take medication with fruit juices for this reason. Obviously if someone is taking recreational drugs with juice, than they may well have to adjust the dose they are taking. If it is true that juices increase the effect of a given dose of mephedrone
, then swiy should experiment with a dose that is less than his/her usual amount!