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  #1  
Old 03-04-2010, 14:32
keylogger614 keylogger614 is offline
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methadone and grapfruit juice

i just had a very big question. is it true that mixing methadone with (white 100%) grapfruit juice makes the effect stronger, and what is the vitamin or other chemical in this drink that makes it happen, and can it be found in other juices and or vitamin pills. Because i myself cannot stand grapefruit juice lolz. so plz if there is sumthin with the same chemical that makes u get off better out can sum one plz tell me?
  #2  
Old 03-04-2010, 15:52
kimotag kimotag is offline
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Re: methadone and grapfruit juice

Grapefruit juice (and other juices) are known to effect the absorption of drugs, by interfering with the enzymes that break down substances in the stomach. Sometimes more of the drug will get into the system as a result. Other juices such as apple have a similar effect, but bear in mind that juices can do the opposite with some drugs, reducing the effects of a given dose!
Doctors advise not to take medication with fruit juices for this reason. Obviously if someone is taking recreational drugs with juice, than they may well have to adjust the dose they are taking. If it is true that juices increase the effect of a given dose of mephedrone, then swiy should experiment with a dose that is less than his/her usual amount!
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Old 05-04-2010, 15:14
Jasim Jasim is offline
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Re: methadone and grapfruit juice

This topic has been covered. Please use the forum search engine before posting new threads.

See: Effects of grapefruit juice on the pharmacokinetics of the enantiomers of methadone.

And:Grapefruit juice potentation with methadone

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excellent redirect to the relevant area
Nicely said, excellent redirect. This is how it's done.
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Old 05-04-2010, 15:38
Ilsa Ilsa is offline
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Re: methadone and grapfruit juice

thank you, jasim. closed.
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