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Unidentified Products Unidentified research chemical products

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Old 25-09-2010, 00:27
orangity orangity is offline
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4-Meppp & PAL-287

SWIM has samples of 4-MePPP and PAL-287, swim has no information on these chemicals except the PAL-287 wikipedia page . Both samples are pure white in color. What kind of effects should be expect? Are these dangerous when consumed?

Any info appreciated
Old 29-09-2010, 13:01
JustWantingHighs018 JustWantingHighs018 is offline
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Re: 4-Meppp & PAL-287

Yeah I have the same samples from the same vendor. I don't know If I want to try them out also being that there is no info on them on the web
Old 29-09-2010, 16:16
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Re: 4-Meppp & PAL-287

If you're going to start a drug info thread, and you've seen there is info on wikipedia, you could at least share that info in your post. From wikipedia:
Naphthylisopropylamine (PAL-287) is an experimental drug currently under investigation for the treatment of alcohol and stimulant addiction.

Naphthylisopropylamine acts as a non-neurotoxic releasing agent of serotonin, norepinephrine, and dopamine, with EC50 values of 3.4 nM, 11.1 nM, and 12.6 nM, respectively. It also has affinity for the 5-HT2A, 5-HT2B, and 5-HT2C receptors (EC50 values = 466 nM, 40 nM, and 2.3 nM, respectively), and acts as a full agonist at 5-HT2B and as a partial agonist at 5-HT2C, while its affinity for 5-HT2A is probably too low to be significant.

In animal studies, naphthylisopropylamine was shown to reduce cocaine self-administration, yet produced relatively weak stimulant effects when administered alone, being a lesser stimulant than d-amphetamine for comparison. Further research is now being conducted in primates to see if it will be a useful substitute for treating drug addiction in humans as well.

An important observation is that in behavioral studies, rodents would consistently self-administer selective norepinephrine and dopamine releasing agents such as d-amphetamine, yet compounds that also release serotonin like naphthylisopropylamine would not be self-administered.

Systematic (IUPAC) name
CAS number 18085-03-5
ATC code None
PubChem CID 10219723
ChemSpider 8395215
Chemical data
Formula C13H15N
Mol. mass 185.27 g/mol
SMILES eMolecules & PubChem
Synonyms 1-(2-naphthyl)-2-aminopropane; alpha-methylnapthylethylamine
Therapeutic considerations
Pregnancy cat. ?
Legal status Uncontrolled
Routes Oral

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1-(2-naphthyl)-2-aminopropane, 4-meppp, alpha-methylnapthylethylamine, drug, naphthylisopropylamine, norepinephrine, pal-287, ppp

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