I thought Ru posted on this before, but I can’t find it. Perhaps it was on crack
Anyway, From R.B.C.:
Volunteers were given 70mg of Heroin
via intravenous infusion. In the 40 hour urine approximately 45% of the dose was recovered as urinary metabolites: 4.2% Morphine
, 38.3% Conjugated Morphine, 1.3% 6-Acetylmorphine and 0.1% unchanged Heroin. Morphine was excreted mainly in the early hours of the study and very little was found after 12 hours had passed. Maximum urine concentrations of total Morphine averaged 116 mg/L between 5.6 and 8.6 hours following the start of the 7 hour infusion (Elliot et al., 1971). 6-Acetylmorphine is present in urine in 64-73% of all Heroin users studied, averaging approximately 0.8 mg/L and ranging up to 10 mg/L (Fehn and Megges, 1985; Derks, et al., 1986). Urinary elimination half-lives averaged 0.6, 4.4 and 7.9 hours for 6-Acetylmorphine, Morphine and Conjugated Morphine, respectively, in 6 volunteers given a single 6 mg intramuscular H dose (Cone et al., 1991).
E.J. Cone, P. Welch, J.M. Mitchell and B.D. Paul. Forensic drug
testing of opiates
: I. J. Anal. Tox. 15: 1-7, 1991.
H.J.G.M. Derks, K Van Twillert, D.P.K.H. Pereboom-de Fauw et al. Determination of the heroin metabolite 6-acetylmorphine by high-performance liquid chromatography using automated pre-column derivatization and fluorescence detection. J. Chrom. 370: 173-178, 1986.
H.W. Elliot, K.D. Parker, J.A. Wright et al. Actions and Metabolism of heroin administered by continuous intravenous infusion to man. Clin. Pharm. Ther. 12: 806-814, 1971.
J. Fehn and G. Megges. Detection of 06-monoacetylmorphine in urine samples by GC/MS as evidence for heroin use. J. Anal. Tox. 9:134-138, 1985.