I know the bioavailability of oral oxycodone
IR is pretty high (something like 60% to 87%), but what is the bioavailability of the same oxycodone IR if crushed, mixed with water in a spoon, sucked up in a syringe through a tiny cotton ball, and injected intramuscularly? Would SWIM
get more of the active ingredient since it is bypassing the liver (which would destroy a lot of it) or would SWIM get less of the active ingredient because essentially pills are made to be swallowed and not intended for injection? SWIM definitely feels euphoria
from both methods but it's hard to tell which ROA has a higher BA and lasts longer. Thanks in advance for your knowledgeable and valuable answers.