Perhaps some of you have seen my other threads. Long story short: long time insomniac, using mirtazapine
for years and years, was using SH*TTY Mylan
mirtazapine for about a year and experiencing minimal relief from insomnia. Recently discovered and got my old Teva brand mirtazapine and have gotten a good deal of relief from insomnia. I am also on 0.5 mg clonazepam
per day taken along with mirtazapine before bed.
Problem is I still wake up exactly 4.5 hours after I fall asleep and take 0.5-1 mg lorazepam
to fall back asleep. Or else I go through strange alternations of sleep with half-awake, half-dreaming states for the next 2-4 hours and wake up feeling like shit. I hope to at least get a better second half of sleep if not eliminate my other medications by using baclofen (lioresal)
. I would like to get rid of mirtazapine even if for no other reason than being unable to stop eating.
I have been reading about baclofen and its ability to increase delta-sleep and stop nighttime awakenings. Apparently in the right dose it is the closest legal thing to GHB
due to its interactions with GABAb receptors. It was even somewhat successfully used to treat narcolepsy (http://www.ncbi.nlm.nih.gov/pubmed/19520267
). I talked to my psychiatrist today and even brought in multiple articles showing its effects on sleep. He absolutely refuses to prescribe it on any condition.
Since I cannot get the drug
, a friend of mine on the same medications with the same problem would obtain the drug from a reliable foreign pharmacy and experiment on himself.
I've read the articles on this site about baclofen and realize that: 1) It can be dangerous in combination with other CNS depressants
like mirtazapine and clonazepam, 2) Benzos
and Baclofen work differently and withrawal from one might not be relieved by the other and 3) In certain doses (not sure if too much or not enough) it causes insomnia and perhaps some euphoria
like GHB at lower doses. I have relayed this to my friend. He will eliminate mirtazapine and lorazepam while experimenting, at least at first.
Here is my specific question to the board: what dose is best for inducing sleep? Does anyone here have any experience using it, especially using it once or twice a night rather than continual dosing? My friend would really like to know, since his plan is to start at 20mg once per night.
AZ8990 added 2 Minutes and 23 Seconds later...
This study is useful as well: http://www.ncbi.nlm.nih.gov/pubmed/6721446