What causes this specific opiate
withdrawal symptom? Frequent Urination
symptom which probably has nothing to do with the brain is the frequent urge to urinate during withdrawal.
During withdrawal I really often have to go to the toilet. In order to find a (herbal?) remedy, I want to understand how this happens.
Maybe it can be explained when I understand the cause of the urinary retention caused by opioids
. But I cannot find anything about this, too. Why do you have to urinate so often in withdrawal?
(Together with the sweating causes this probably a greater loss of fluid and electrolytes. What is the best way to compensate this? Drinking much water? Could cause even more sweating and cannot compensate electrolyte loss. - Drinking green tea? Good because of flavonoids? Bad because of coffeine? - Electrolyte drinks? Homemade recipe?)
As I looked up "Vasopressin" in another case, I found that it is also called "antidiuretic hormone" (ADH). I alwasy thought that it plays a role in inflammation and blood pressure.
But the first sentence in the english version of wikipedia is:
One of the most important roles of AVP is to regulate the body's retention of water; it is released when the body is dehydrated and causes the kidneys to conserve water, thus concentrating the urine and reducing urine volume.
and later on I found a short remark
In the perioperative period, the effects of surgical stress and some commonly used medications (e.g., opiates, syntocinon, anti-emetics) lead to a similar state of excess vasopressin secretion. This may cause mild hyponatremia for several days.
So opiates seem to be responsible for an augmented release of the antidiuretic hormone. Can this be the cause of the urinary retension? Why is is mainly a problem when somebody starts to take opioides? After a time of regularly use, it seems that nearly nobody has this problem anymore.
Does the body gets acclimated to the augmented ADH release in some way? I have no theory what happens during withdrawal but it looks like as there could be a connection between ADH secretion and the frequent urinations during withdrawal.
Maybe there are some plants that can also lead to vasopressin secretion (but in a lighter way as opioids)? That could possibly help..?
Who knows something about that?