Originally Posted by Davidazors
Also is 2000mg apap
dangerous in one dose? SWIM
has done it before without falling into acute kidney failure luckily, but was thinking of doing a CWE to give his kidneys a break. If he did a CWE would that make the drugs
more potent/dangerous due to the fact they may enter the blood stream faster?
First of all, taking any dose of APAP over 1000mg is unwise.
2,000mg might not send you into acute liver failure (large doses of APAP are more of a concern for your liver than kidneys), but it's really a toxic substance when taken in that amount. Therefore, any time the APAP in your dose amounts to more than 1000mg, you should be performing a CWE.
It's really that simple. Doing a CWE on those pills won't really make them any more potent or reach your blood stream any faster. With the oxycodone
dissolved in liquid it may kick in a few minutes sooner than still in pill form, but really not that much.
The obligatory warning here is that mixing CNS depressants
is never safe.
In all reality, you're better (safer) off taking the 25mg of oxy after performing a CWE and enjoying a lesser buzz.
If you are determined to mix them, though, I would either not take both of those T3s or not take the full 25mgs of oxycodone. Even though 60mg of codeine
is equivalent to only about 6mgs of oxy (when taken orally), given the fact you've never combined these two before, it's probably not wise to take everything you have. The overall effects of codeine and oxycodone are very similar to one another when taken at equivalent doses. In the amounts you're talking about, based on your experiences, adding the codeine would probably just boost whatever oxy you take to feel like a slightly higher dose. That being said, I still recommend against it because you never know how you'll react to a new drug
and combining it with another as potent as oxycodone is not necessarily the smartest idea. Just my two cents.