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  #1  
Old 13-05-2006, 10:44
Kalagast Kalagast is offline
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A question about MDMA's affects on the renal system

I have read from a few sources (Lycaeum, etc.) that MDMA produces some strain on liver, heart, and kidney function. I'm mostly interested in the latter of these, but I'm having a difficult time finding any information on MDMA's affects on the kidneys in abundance.

I'd be very grateful if anyone could provide me with some links or information about this. Specifically, I'm wondering if it would be significantly dangeorus for someone with only one kidney to ingest MDMA.
  #2  
Old 13-05-2006, 20:28
Unsolved Unsolved is offline
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Everything you ingest from drugs to certin foods can strain all these systems not just mdma. The body has to break everything down that you ingest which causes this internal strain. However I'm sure that it does strain these systems to some degree, dose dependant on how much the body is strained of course. Not more then any other susbtance that I'm aware of especially some of the anti rejection drugs used for transplants. These drugs are extremely stressful on the kidney and liver. Plus everyone is a little different, however I venture to guess with almost all normal people the strain is temporary on these organs and the all the organs will return back to normal function upon stopping your roll and getting some rest. As far as having only one working kidney and taking mdma, I just don't know either way. Anyone else out there know????
  #3  
Old 14-05-2006, 00:11
Nagognog2 Nagognog2 is offline
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I would suggest that you get in touch with your veterinarian regards the rat you met that has one kidney and enquire the dangers of giving it an amphetamine. An amphetamine is what you are speaking of here. If those with one kidney can tolerate an occasional amphetamine ride - there should be no problem. If rats with one kidney as contra-indicated for such - then steer clear.

Where is our pet veterinarian when we need him....growl...sets loose the Flying Monkeys...
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Old 14-05-2006, 16:40
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Nagognog2 I like that "set loose the flying monkeys..." lol
  #5  
Old 15-05-2006, 20:56
Richard_smoker Richard_smoker is offline
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There are actually a couple of things that you need to clarify before you can acurately get the response that you are seeking...

First of all, YES--MDMA DOES have effects on the kidneys. It is an ADH (anti-diuretic hormone) agonist: therefore, it can actually cause people to OVER-hydrate and these are the only reported deaths (that I'm aware of--actually according to SWIM's friend who plans on experimenting with MDMA and end-of-life care.)

The most important question that is bothering me is this: Why do you only have one kidney? did you donate one to a relative? do you have renal failure/polycystic kidney disease, or what?

Also, how OLD you are is pretty important as well. That makes me think either congenital malformation (like horshoe kidney or something like that) vs. you donated a kidney to a relative... Very different things.

However, you must realize that you CAN NOT over-drink your water if you do, indeed, decide to try this drug. I know that this stands in the way of every suggestion i've ever seen to people in regard to taking MDMA, but in YOUR case, just a small amount of ADH coupled with too much water could cause you to actually DIE from the xtc.

BTW, ADH, desmopressin, and vasopressin are all the same thing. I just can't recall if xtc causes a release of ADH or if it just acts like ADH on the kidneys... This is a hot topic right now in medical advice and harm-reduction. especially if it's true that the only deaths were due to overhydration.
  #7  
Old 12-08-2014, 03:34
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Re: A question about MDMA's affects on the renal system

i'm gonna take a guess that this might be the appropriate place to pose this question-

a friend of a friend's doctor ordered some routine lab work for them & it came back showing their kidneys functioning at a slightly lower rate than normal so their doctor is ordering more tests...

this person apparently only indulges in mdma every couple of months or so, yet has been for several years. is it possible that the mdma use has affected their kidneys & if so, what helps kidneys get back up to speed, so to speak?
  #8  
Old 12-08-2014, 05:58
Damocles Damocles is offline
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Re: A question about MDMA's affects on the renal system

This is an extremely old thread, but any temporary loss of kidney function due to MDMA causing the release of vasopressin should be gone soon after discontinuation of MDMA and its last dose. Probably a day or so.

Vasopresssin causes the kidneys to not pass as much fluid and is a normal reaction in the short term, but shouldn't cause long-term problems.

That's not to say that long-term use/abuse or potential adulterants might also be an issue with normal kidney function. It's very complicated as to exactly what could be causing reduced kidney function, and without knowing full lab results, it would only be guess work. Additionally there may be other factors one might be exposed to, such as infection or other substances, not necessarily drugs but also diet which might also adversely affect kidney function.

Caffeine is especially hard on the kidneys as well, so if you consume a lot of caffeinated beverages or coffee, this could also impact normal kidney function as well, people with poor kidney function are discouraged from consuming beverages containing lots of caffeine.

In short, it's next to impossible to diagnose over the Internet, especially without knowing a complete medical history and full test results over a given time span.

Be responsible...

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ecstasy, ecstasy effects, effects of ecstasy, mdma, mdma and hepatic function, mdma and kidneys, mdma and liver, mdma and renal function, mdma effects, mdma side effects

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