1.Yes it does potentate the effects of hydrocodone
. I would drink 16 oz. 10 minutes before taking the hydrocodone. I suggest getting a whole grapefruit and juicing it yourself. It seems to work a lot better,and is actually pretty damn good for you(While tasting pretty awesome.).
2. Unfortunately,since it would past the first metabolism,yes,it does negate the juice if you plug the pills.
3.What I would do,is either drink 16 oz. of juice,or juice a grapefruit,drink it 10 minutes beforehand, Take 30-60mgs of DXM
30 minutes beforehand(Great Potentator/Tolerance Reducer),and take 2-4 tums with the dose,orally.(increases how long it takes for the drug
to digest=more drug actually in your system.) This should amplify the effects greatly(I mean 50-75% In my experience,if not greater)
With this you should be able to take only 2.5mg of Hydrocodone orally,and expierence ~5mg of hydrocodone effects. Unless you need more then the ~5mg for your pain relief,you should be good,and get up to four doses out of those two pills.
Hope you have a good day!
P.S.: Please don't say "anyone??" Only 60 minutes after starting a post,sometimes questions can linger for days,even weeks without response,and if you do that it just seems slightly rude,even though I do understand! Remember,be patient and take drugs
AFTER the question is answered if possible!