Drugs-Forum  
Home Wiki Studies Forum Groups Blog Video Images News
Go Back   Drugs Forum > DRUG-FORUMS > Research Chemicals > Beta-Ketones
Mark Forums Read
Register Tags

Notices

Beta-Ketones Mephedrone, Methylone, Butylone, Methedrone, Ethcathinone, 3-fluoroMethCathinone (3FMC), Methylenedioxypyrovalerone (MDPV)

 
Thread Tools
  #1  
Old 09-02-2014, 14:25
JTC3889 JTC3889 is offline
Silver Member
 
Join Date: 07-09-2007
Male from United States
Posts: 223
JTC3889 is captain of the psychonauts.JTC3889 is captain of the psychonauts.
Points: 265, Level: 2 Points: 265, Level: 2 Points: 265, Level: 2
Activity: 0.2% Activity: 0.2% Activity: 0.2%
best legal replacement for a-pvp USA

As you might have seen, I posted a thread that stated that 10 beta-ketones are being temporarily scheduled (1) including a-pvp. I would like to get any feedback on what is still legal that would give that feeling that a-pvp and previously MDPV created, and which can also be vaporized as a salt. Preferably something related to the "PV's" and more distantly perhaps the "pentedrones" as I remember it stated. Any feedback is good feedback.
  #2  
Old 10-02-2014, 17:07
chemman chemman is offline
Silver Member
 
Join Date: 16-05-2008
Male from United States
Posts: 30
chemman is captain of the psychonauts.chemman is captain of the psychonauts.chemman is captain of the psychonauts.
Points: 45, Level: 1 Points: 45, Level: 1 Points: 45, Level: 1
Activity: 0% Activity: 0% Activity: 0%
Re: best legal replacement for a-pvp USA

At the moment, the best replacement for MDPV and a-PVP is a-PHP. On the internet I found information: a-PHP is better than MDPV and PVP.

Full name alpha-PHP: 1-Phenyl-2-(1-pyrrolidinyl)-1-hexanone

  #3  
Old 10-02-2014, 18:38
JTC3889 JTC3889 is offline
Silver Member
 
Join Date: 07-09-2007
Male from United States
Posts: 223
JTC3889 is captain of the psychonauts.JTC3889 is captain of the psychonauts.
Points: 265, Level: 2 Points: 265, Level: 2 Points: 265, Level: 2
Activity: 0.2% Activity: 0.2% Activity: 0.2%
Re: best legal replacement for a-pvp USA

That is wonderful; forget a-pvp, but it's supposedly better than MDPV, that's remarkable.
I have one reservation about this compound, however. The para-methylated version of this chemical is MPHP, MPHP can lead to serious poisoning with toxic liver damage and rhabdomyolysis. And since they are only one carbon away from being identical, molecularly, then we must consider this possibility before trying it at least until it is proven, or even until a general consensus is reached among potential users. And if anyone thinks they can find any data on this, post it ASAP! Someone should make a drug info page on a-PHP if it hasn't been done already.
And last I will say that I am on my knees praying that this stuff is safe, and legit. Otherwise this ban may take a toll on me for a good while, as I am a regular user of a-PVP and if this new stuff doesn't check out, I'm fucked.
  #4  
Old 10-02-2014, 19:24
chemman chemman is offline
Silver Member
 
Join Date: 16-05-2008
Male from United States
Posts: 30
chemman is captain of the psychonauts.chemman is captain of the psychonauts.chemman is captain of the psychonauts.
Points: 45, Level: 1 Points: 45, Level: 1 Points: 45, Level: 1
Activity: 0% Activity: 0% Activity: 0%
Re: best legal replacement for a-pvp USA

According to academic studies, para-methylated derivatives may cause liver failure as a sad side effect, eg. MPHP (MePHP), pyrovalerone, MPPP (MePPP) because of metabolism of these derivatives: the para-methyl functional group is metabolised by cytochrome P450 which leads to toxic metabolites.
This problem does not apply to derivates without para-methyl group as alpha-PVP, alpha-PPP and alpha-PHP. So I think there's nothing to worry about, Your liver shouldn't suffer that much : )

More information:

Peters, FT; Dragan, CA; Kauffels, A; Schwaninger, AE; Zapp, J; Bureik, M; Maurer, HH (2009). "Biotechnological synthesis of the designer drug metabolite 4'-hydroxymethyl-alpha-pyrrolidinohexanophenone in fission yeast heterologously expressing human cytochrome P450 2D6--a versatile alternative to multistep chemical synthesis". Journal of analytical toxicology 33 (4): 190–7

Sauer, C.; Hoffmann, K.; Schimmel, U.; Peters, F. T. (2011). "Acute poisoning involving the pyrrolidinophenone-type designer drug 4′-methyl-alpha-pyrrolidinohexanophenone (MPHP)". Forensic Science International 208 (1–3): e20–e25.

Post Quality Evaluations:
Informative and knowledgeable

Last edited by chemman; 10-02-2014 at 20:48.
  #5  
Old 12-04-2014, 17:18
JTC3889 JTC3889 is offline
Silver Member
 
Join Date: 07-09-2007
Male from United States
Posts: 223
JTC3889 is captain of the psychonauts.JTC3889 is captain of the psychonauts.
Points: 265, Level: 2 Points: 265, Level: 2 Points: 265, Level: 2
Activity: 0.2% Activity: 0.2% Activity: 0.2%
Re: best legal replacement for a-pvp USA

chemman, can you give some more info to support your claim that a-php is both stronger that a-pvp as well as mdpv?

Last edited by Phenoxide; 12-04-2014 at 17:19. Reason: superfluous quote removed

Share this on:

Tags
a-pvp, ban, mdpv, replacement drugs

Thread Tools


Similar Threads
Thread Thread Starter Forum Replies Last Post
USA :What If All Drugs Were Legal ? robert whitfield Miscellaneous News 3 09-11-2007 05:24

» New Threads
How to separate kavalactones from...
Last post by Cousin Merle
1 Replies, 54 Views
Genuine question: What's good...
Last post by m314
19 Replies, 1,426 Views
What's the strongest ecstasy pill...
Last post by stayhappy
0 Replies, 5 Views
How does XR feel versus IR?
Last post by akstallion
0 Replies, 60 Views
Gabapentin (Neurontin)
Last post by akstallion
90 Replies, 73,861 Views
Does this new blanket ban of legal...
Last post by Smeg
37 Replies, 1,579 Views
LSD in urine tests?
Last post by stayhappy
2 Replies, 31 Views
Diethyl ether the misunderstood...
Last post by Trosiv
13 Replies, 813 Views
Will My Brother Ever Get Back To...
Last post by 5-HT2A
30 Replies, 2,618 Views
The Blood Brain Barrier & Drugs...
Last post by prescriptionperil
3 Replies, 238 Views
» New Wiki Articles
CBD

Sitelinks: Information:

All times are GMT +1. The time now is 03:30.


Copyright: SIN Foundation 2003 - 2014, All rights reserved