Drugs-Forum  
Home Wiki Studies Forum Groups Blog Video Images News
Go Back   Drugs Forum > DRUG-FORUMS > Opiates & Opioids
Mark Forums Read
Register Tags

Notices

Opiates & Opioids Opiates & Opioids.

 
Thread Tools
  #1  
Old 22-02-2007, 04:36
abba2 abba2 is offline
Account Awaiting Email Confirmation.
 
Join Date: 17-02-2007
92 y/o Male
Posts: 5
abba2 is an unknown quantity at this point
Points: 15, Level: 1 Points: 15, Level: 1 Points: 15, Level: 1
Activity: 0% Activity: 0% Activity: 0%
LD50 - Hydrocodone

SWIM has never heard of LD50 before reading a post here and tried to look up hydrocodone's LD50.

As far as SWIM understands LD50 is the min. amount given to a certain animal that kills the animal.

SWIM read something about 300mg of Hydro for a Rat however that doesn't seem possible. Most people would OD taking 30 10mg esp. without tolerance.

Anyone have a more accurate LD50 or read any other studies on what amount sends a non-tolerant animal or person into an OD or death off Hydro?
  #2  
Old 22-02-2007, 04:54
Nagognog2 Nagognog2 is offline
Banned
 
Join Date: 01-02-2005
Male
Posts: 7,174
Nagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPAC
Points: 3,186, Level: 8 Points: 3,186, Level: 8 Points: 3,186, Level: 8
Activity: 0% Activity: 0% Activity: 0%
Re: LD50 - Hydrocodone

LD50 infers the amount used in 100 test animals. People are generally excluded from this sort of experimentaion (though with Bush in the White House...). It means that 50 of 100 - or the statistical equivalent - died. It does not mean the other 50 walked away unscathed. There could well have been horrible damage done, but they lived. Sort of.

Rats, and other rodents, have a hyper-metabolism - making results very difficult to compare to a human being. So I would tend to agree that 300mg of hydrocodone would likely kill someone without tolerance to opiates.
  #3  
Old 08-03-2007, 04:56
Chunkz Chunkz is offline
Banned
 
Join Date: 01-03-2007
34 y/o Male
Posts: 41
Chunkz needs to UTFSE some more before posting.
Re: LD50 - Hydrocodone

well i dont know if you are thinking about pure hydro, but if you are wondering about vicoden,vicoprofen,lortab,generics,ect.. that contain hydro they also contain acetaminophen which cause liver failer at high doses. Just because one canot servive on a bunch of vic,lor,etc.. doesnt mean they couldn't servive on alot of hydro. Im just asuming youa re not aware because you stated something about taking around 30 10mg tabs, because hydro only comes in legal preps with par..,ibu..,etc.. enless you are using the
"cold extraction method" (for ace..)

Share this on:

Tags
acetaminophen, hydrocodone, hydrocodone overdose, ld50, ld50 of opiates, lortab, opiate, opioid, opioids, toxicity

Thread Tools


Similar Threads
Thread Thread Starter Forum Replies Last Post
Hydrocodone Nanashi Drug Articles 4 16-06-2014 18:57
Combinations - hydrocodone and welburtin interaction. does it block the hydrocodone? andrewcbru Hydrocodone 1 13-10-2012 22:18
Health - Hydrocodone + acetaminophen causes profound hearing loss eltimmy Opiates & Opioids 0 29-09-2007 23:35

» New Threads
Diethyl ether the misunderstood...
Last post by LucySkyDiamands
10 Replies, 589 Views
Question regarding Xanax
Last post by insane3511
4 Replies, 189 Views
How hard it is to quit cold turkey?
Last post by DiabolicScheme
6 Replies, 376 Views
Questions about MDMA/Methylone...
Last post by Reason4rhyme
0 Replies, 71 Views
SNRI and Rhodiola
Last post by DiabolicScheme
2 Replies, 332 Views
Tasmanian Purple/white
Last post by Char1324
4 Replies, 430 Views
What does a morphine/heroin...
Last post by Finely
22 Replies, 111,457 Views
when xanax stops working...
Last post by senorlou
3 Replies, 249 Views
Interesting scholarly drug facts
Last post by DTaggart
26 Replies, 64,015 Views
Kratom for opiate withdrawals?
Last post by DiabolicScheme
2 Replies, 277 Views
» New Wiki Articles
CBD

Sitelinks: Information:

All times are GMT +1. The time now is 02:46.


Copyright: SIN Foundation 2003 - 2014, All rights reserved