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These medications are known to cause adverse events which can contribute to violence such as hallucinations, agitation, emotional instability, violence, paranoia, etc.
These adverse events are clearly labeled on the FDA approved prescribing information leaflet for the medication. These labels often contain confusing medical terms and Dr. Dolan explains in plain English what these adverse events means.
Although the psychiatric advertising jargon of the chemical imbalance in the brain theory is widely promoted, Dr. Dolan points out that there are no biological markers for mental disorders. There are no physical tests done to measure someone's brain chemistry.
Depression is widely associated with the neurotransmitter serotonin however, there is no standard by which one can measure an abnormal serotonin level.
Additionally, SSRI (Selective serotonin reuptake inhibitors) as well as other psychiatric drugs show an affect in the brain during brain scans whereas psychiatric diagnosis don't.
Decstar added 6 Minutes and 58 Seconds later...
Please take this seriously. I was prescribed this medication and this happened to me. I am certain I would have got into serious trouble if I hadn't have stopped taking them and I am lucky I didn't get into trouble. There are much better ways of dealing with depression than taking drugs, believe me.
Last edited by Decstar; 17-02-2009 at 05:52.
Reason: Automerged Doublepost
when swim was taking venlafaxine he got violent...... once he went to attack someone with a screwdriver swim wouldn't normally do anything like this and was only taking the drug a few days when he stopped taking it the anger and violene went away
Swim was never violent on SSRIs but he found them to be very depersonalizing. However, there many indications that this group is drawing uneducated conclusions from raw data. According to Scientific American, 10% of Americans are on anti-depressants; that's over 30 million people. Lets say that there are 1,000 acts of violence cases attributed to anti-depressants every year, that's only 0.003% of cases! Even if there is enough correlative evidence to investigate further, does this not seem like a rather rare occurrence?
After checking out the video and the cached website, it was fairly obvious that the angle here is against conventional medicine and psychiatric treatment. Based the editorial tone alone, I'd suggest being fairly skeptic of the information they've presented.
Most importantly, lets not forget why people are prescribed antidepressants in the first place. Obviously, they are given to people with preexisting psychiatric conditions. Wouldn't it be difficult in these cases to determine precisely if the drug was the root cause?
Finally, in swim's opinion the vast majority of these cases fall under the "It wasn't me, it was the drugs argument". Remember the Toyota accelerator thing earlier this year? Well it so happened that when studied closer, they found that the majority of "accelerator sticking" problems were due to bad drivers pushing on the wrong pedal. This is why you don't make conclusions based on raw data, especially if it's anecdotal.
Last edited by Code9; 02-10-2010 at 00:45.
Swim only ever felt agitated while on fluoxetine/Prozac, and it took 2-3 days for that effect to become a worry. Swim stopped the medication before doing or saying anything he could regret. Swim has been prescribed the other SSRIs but didn't take them longer than a day or two due to unwanted stimulant/agitant side effects and insomnia. He reacts strangely to quite a few drugs so he just thought this was his own weird reaction. He tried the Prozac on two more occasions after the first agitated reaction but couldn't keep taking it due to the same reason.
This is just swim's reaction to SSRIs however. He would never tell others not to take their medication if it is helping them. Some people seem to report the opposite side effects from SSRIs, such as emotional dulling, and doctors that swim has seen have said they believe these drugs are useful for symptoms such an anxiety aswell as depression. It just shows that everyone reacts individually to particular medications.
Obviously SSRIs and SNRIs are not appropriate medications to treat depression with in the first place simply based on the their mechanism of action.
More serotonin? So what. That's pointless if that serotonin is interacting with serotonin receptors that are producing negative effects at the same time others are producing positive ones.
SSRIs and SNRIs provide more serotonin binding for EVERY serotonin receptor site. We understand through research on serotonin receptors that agonist activation of each does not necessarily produce a "positive" behavioral effect. In fact, agonism of most serotonin receptors, barring 5-HT1a of course, can easily worsen anxiety and depression until those receptors down regulate with long term treatment.
Furthermore, the distribution of the various receptors in different areas of the brain could help explain the paradoxical reactions some people have to SSRIs/SNRIs. Why do some people have intense nausea on SSRIs/SNRIs and others don't have any at all? 5-HT3 receptor distribution is the likely culprit.
The same idea could be applied to aggression and violence produced by the drugs, which just don't necesarily yet understand which receptors are involved and what signaling cascades are taking place to produce these types of behavioral responses.
Ive known this for a while. The lady that drowned her 5 children was prescribed Prozac and sometime right before she did that her doc. cut her dosage. As far as I know those kinds of things didn't happen way back when. And no one even thinks about what role the medications play in it.
Ive known this for a while. The lady that drowned her 5 children was prescribed Prozac and sometime right before she did that her doc. cut her dosage.
Surely the lack of medication isn't to blame for her violent behavior! Before Big Pharma started pushing these dangerous drugs, everyone lived happily in peace and harmony!
(Not saying that's what you were implying, FreeBliss, but that's what the video seems to argue.)
When I looked up this Medical Accountability Network, I found Moira Dolan's comments on Andrea Yates, who was on twice the maximum dosage of venlafaxine, and was taken off haloperidol shortly before she killed her children.
This network and Dr. Dolan are also cited on anti-vaccine websites, some kind of anti-drug "natural solutions" website, and apparently were involved in an anti-ECT protest, so I doubt their credibility, to put it mildly.
I would just like to add my personal experience for whatever it's worth: I was on anti-depressants for about 4 years (17-21) and never experienced any kind of violent tendencies or suicidal thoughts caused by the anti-depressants (sure, I've had many thoughts of suicide but they were not A-D related because I had the same thoughts before I started on them). I've been on Paxil, Trazadone, and Prozac in that order. Prozac worked the best for my depression but was faaarrr from a cure. The only effect it had on my anxiety was keeping me from going into full-blown panic attacks. I could be right on the edge but I'd never fall off. Again, I just wanted to give my personal experience.
I did however have a friend who was on Chantix (anti-smoking drug but an SSRI) and he told me he had very violent thoughts. He was noticeably withdrawn and rarely spoke or went out of the house. He told me he had thoughts of killing his roommate and then killing himself. He quit taking it once he realized what was going on. Funny thing though, while on it, he went from 30-40 cigarettes a day to 5-10! Go figure.
SWIM took Citalopram on and off (20 mg-40 mg) for 7 years up to last June and they had suicidal ideation and anhedonia fairly often. Before they stopped taking it for the last 6 months they had severe paranoia which carried over into even their dreams and they were convinced everyone wanted to kill SWIM to the point they were planning on purchasing a gun. After they stopped taking citalopram the paranoia subsided. They took Bupropion (500 mg) for about 8 months which only made them neurotic. About ten years ago the rabbit was put on a cocktail of Paroxetine, Valproic Acid and Olanzapine (based on a schizophrenia misdiagnosis) which resulted in fullblown psychosis and violent behavior for the month and half they took it before almost getting arrested at school when they attacked the principal for no good reason, after which SWIMs parents finally took them off all meds.
Given their experience, SWIM has absolutely zero faith in SSRIs. The only reliable "anti-depressant" for SWIM has been daily rigorous exercise, which despite not helping much with anxiety eliminates any depressed thoughts while at the same time providing much more lucidity compared to SSRIs.