Drugs-Forum  
Home Wiki Studies Forum Groups Blog Video Images News Chat
Go Back   Drugs Forum > DRUG-FORUMS > Downers and sleeping pills > Benzodiazepines
Mark Forums Read
Register Tags

Notices

Benzodiazepines All about benzodiazepines (downers)

 
Thread Tools
  #1  
Old 18-03-2009, 04:11
Junket Junket is offline
Banned
 
Join Date: 30-07-2008
25 y/o Male
Posts: 490
Blog Entries: 3
Junket is an unknown quantity at this point
Alprazolam & Antibiotics

sooo swim did a search but didnt find anything on it directly......

is it alright to mix the two?

swim gets his wisdom teeth out tomorrow and was hoping to be really high afterwards just laying in bed....

he has never done it. was gonna take .5mg or 1mg and just go with it
  #2  
Old 19-03-2009, 07:43
Jatelka Jatelka is offline
Psychedelic Shepherdess
 
Join Date: 16-10-2005
39 y/o Female from United Kingdom
Posts: 5,483
Jatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond repute
Points: 10,860, Level: 15 Points: 10,860, Level: 15 Points: 10,860, Level: 15
Activity: 0% Activity: 0% Activity: 0%
Re: Alprazolam & Antibiotics

Depending on the antibiotics, there may well be an interaction, if they are inhibitors of CYP3A, such as the macrolides clarithromycin and erythromycin (although these would be extremely odd choices post tooth extraction).

Cytochrome inhibitors such as erythromycin could increase avalability of Alprazolam theoretically, but an abstract I found suggests that even though it inhibits CYP3A, erythromycin does NOT result in increased psychomotor side effects of Alprazolam (and, I guess, by inference, may not increase cognitive effects)

A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism
Clinical Pharmacology and Experimental Therapeutics 1996 May;59(5):514-9
Yasui et al
  #3  
Old 19-03-2009, 17:44
Junket Junket is offline
Banned
 
Join Date: 30-07-2008
25 y/o Male
Posts: 490
Blog Entries: 3
Junket is an unknown quantity at this point
Re: Alprazolam & Antibiotics

Quote:
Originally Posted by Jatelka View Post
Depending on the antibiotics, there may well be an interaction, if they are inhibitors of CYP3A, such as the macrolides clarithromycin and erythromycin (although these would be extremely odd choices post tooth extraction).

Cytochrome inhibitors such as erythromycin could increase avalability of Alprazolam theoretically, but an abstract I found suggests that even though it inhibits CYP3A, erythromycin does NOT result in increased psychomotor side effects of Alprazolam (and, I guess, by inference, may not increase cognitive effects)

A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism
Clinical Pharmacology and Experimental Therapeutics 1996 May;59(5):514-9
Yasui et al
  #4  
Old 19-03-2009, 20:15
Jatelka Jatelka is offline
Psychedelic Shepherdess
 
Join Date: 16-10-2005
39 y/o Female from United Kingdom
Posts: 5,483
Jatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond reputeJatelka is a true resource and beyond repute
Points: 10,860, Level: 15 Points: 10,860, Level: 15 Points: 10,860, Level: 15
Activity: 0% Activity: 0% Activity: 0%
Re: Alprazolam & Antibiotics

^^^ ????
  #5  
Old 20-03-2009, 00:28
Junket Junket is offline
Banned
 
Join Date: 30-07-2008
25 y/o Male
Posts: 490
Blog Entries: 3
Junket is an unknown quantity at this point
Re: Alprazolam & Antibiotics

hahaha... just the way you said that was like......... damn.......really?


from what i gathered, there are no risks........

Share this on:

Tags
alprazolam

Thread Tools


Similar Threads
Thread Thread Starter Forum Replies Last Post
Alprazolam Nanashi Drug Articles 18 27-12-2012 19:33
China - Govt curbs overuse of antibiotics enquirewithin Health (News) 0 11-12-2012 05:15
Pharmacology - some CYP3A inhibitors & their effect on alprazolam hateyoul3itch Benzodiazepines 0 09-12-2010 22:12
Pharmacology - Alprazolam Jatelka Benzodiazepines 0 16-08-2007 19:20

» New Threads
"It will never happen to me"...
Last post by ladywolf2012
3 Replies, 109 Views
Attention Floridians
Last post by renacer
23 Replies, 1,330 Views
Didn't miss but felt no rush
Last post by 5moreyearswilldo
1 Replies, 228 Views
A Warning for People With SSRI's...
Last post by Adas
4 Replies, 285 Views
Plastic bottle pipe
Last post by 5moreyearswilldo
3 Replies, 183 Views
Ecstasy and General Health concern
Last post by Potter
5 Replies, 219 Views
Drug Courts Lobbied Against Key...
Last post by Beenthere2Hippie
0 Replies, 14 Views
Senior Citizen Drug Couriers...
Last post by Potter
1 Replies, 30 Views
DMAE tolerance
Last post by Adas
3 Replies, 217 Views
Gold Reserve Legendary extract,...
Last post by ianzombie
8 Replies, 3,572 Views
» New Wiki Articles
GHB

Sitelinks: Information:

All times are GMT +1. The time now is 23:04.


Copyright: SIN Foundation 2003 - 2014, All rights reserved