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2-DPMP, or Desoxypipradrol, is a long acting stimulant drug that functions as an NDRI much like MDPV and Methylphenidate, the latter of which it is an analog of. Its effects include promoting wakefulness, attention, and arousal, however it can also significantly reduce ones ability to fall asleep due to its long duration of action.


[top]Introduction to 2-DPMP

First discovered by CIBA pharmaceutical company (now refered to as Novartis) in the 1950s, 2-DPMP acts as a central nervous system stimulant by means of norepinephrine-dopamine reuptake inhibition. Upon its initial discovery, 2-DPMP was undergoing research as a possible treatment for narcolepsy and ADHD, however further research on the compound was cease upon the discovery of methylphenidate. 2-DPMP has also undergone research as a possible recovery agent for patients awakening from anesthesia, though trials were short and development did not continue.

[top]Using 2-DPMP

[top]Ways of administration

2-DPMP has been proven to be active through a variety of different routes including oral, intranasal, sublingual, and intravenous administration. In terms of its recreational effects, 2-DPMP is most often administered through insufflation, due to its considerably high bioavailability (>90%).

[top]Effects of 2-DPMP


  • Increased concentration
  • Stimulation
  • Euphoria


  • Nystagmus


  • Insomnia
  • Anxiety
  • Tachycardia
  • Hypertension
  • Bruxism

[top]Combinations with 2-DPMP

[top]Different Uses for 2-DPMP

  • 2-DPMP has been investigated as a possible treatment for narcolepsy and ADHD, however research was dropped after the discovery of methylphenidate as the compound proved to be more promising than 2-DPMP.
  • 2-DPMP has also been researched as a possible recovery agent for patients awakening from anesthesia, though trials were short and development did not continue.

[top]Pharmacology of 2-DPMP

Mechanism of actionNDRI
Half-Life16-20 hours

[top]Chemistry of 2-DPMP

Systematic(IUPAC) name:(RS)-2-benzhydrylpiperidine
Synonyms:Desoxypipradrol, 2-DPMP
Molecular Formula:C18H21N, C18H21N.HCl (hydrochloride)
Molar mass:251.37 g/mol, 287.83 g/mol (hydrochloride)
CAS Registry Number:519-74-4, 5807-81-8 (hydrochloride)
Melting Point:no data
Boiling Point:no data
Flash Point:no data
Solubility:no data
Additionnal data:none

[top]Reagent test results of 2-DPMP

Reagent color produced picture video
Marquis Reddish[1] - -
Mandelin Yellow/light green - -
Mecke No reaction[1] - -
Cobalt thiocyanate Pink[1] - -

Originally Posted by NeuroChi View Post
Marquis: yellow
Mandelin: yellow/light green
Mecke: yellow

[top]The dangers of 2-DPMP

Prior to administering 2-DPMP one should review the potential dangers that are associated with the compound.
  • 2-DPMP is a research chemical, thus the effects and side effects of the compound have yet to be established due to a lack of formal trials.
  • 2-DPMP acts as a central nervous stimulants, user whom have a known physical illness should avoid this compound as it may result in dangerous and potentially deadly side effects.
  • 2-DPMP has a very long half-life, thus the drug has been know to stay active from very long periods of time especially when redosing occurs, resulting in several days worth of rather uncomfortable or annoying insomnia.
  • 2-DPMP is a psychoactive substance thus users whom have a known mental illness should avoid this compound as it may result in undesirable side effects.

[top]Producing 2-DPMP

[top]Forms of 2-DPMP

[top]Legal status of 2-DPMP

[top]United Nations




2-DPMP was listed as a narcotic drug without medicinal value as of late 2012.

[top]Other Countries

[top]History of 2-DPMP

Popularity of 2-DPMP over time:

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  1. ^ a b c http://www.reagent-base.net/reagents-table/

Attached Images
File Type: jpg 2-DPMP.jpg (60.7 KB, 157 views)
Created by NeuroChi, 30-03-2011 at 16:24
Last edited by syntheticdave, 26-09-2013 at 23:02
Last comment by John_bob on 13-06-2015 at 21:47
7 Comments, 26,959 Views

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2-diphenylmethylpyrrolidin, 2-dpmp, desoxypipradrol
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