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25B-NBOMe


[top]Introduction to 25B-NBOMe



[top]Introdution

25B-NBOMe is derived from the psychedelic phenethylamine 2C-B (4-bromo-2,5-dimethoxylphenethylamine) by substitution on the amine with a 2-methoxybenzyl (BOMe) group.

The drug is a very potent partial agonist of the 5HT-2A receptor (which belongs to the serotonin group of receptors) giving it its psychedelic effects.

[top]Ways of Administration


Insufflated

(dissolved in water):
Light - 50-200 g (0.05 - 0.2 mg)
Mild - 200-350 g (0.2 - 0.35 mg)
Strong - 350-800 g (0.35 - 0.8 mg)
Very strong - 800 g -1400 g (0.8 - 1.4mg)
Insanity - 1400 g+ (1.4 mg+)

Orally

Plugged

Sublingual

IM/IV

[top]Effects of 25B-NBOMe

Sublingual

Threshold - 100ug
Mild- 100-300
Strong - 350-700
Very strong - 700ug+

Duration:8-10hours
Come Up 1hour+
Plateau 3-4hours

(More information needed to verify dosage)

From liquid insufflation (strong dose):


Extreme patterning
Masses of vibrant coloring
Strong sound distortion - sounds leaking in and out of rooms and into the user
Very strong electric spasmodic body high

Complete ego loss
Loss of self
Loss of location, being, time, space etc

Inability to function at all normally
Slight nausea but passes quickly

[top]Combinations with 25B-NBOMe

[top]Different Uses for 25B-NBOMe



[top]Pharmacology of 25B-NBOMe

25B-NBOMe is a potent and selective partial agonist at the 5-HT2A receptor. [1]


[top]Chemistry of 25B-NBOMe

The following image displays the structural relationship between 2C-B, 2-methoxytoluene, and 25B-NBOMe.



[top]The Dangers of 25B-NBOMe


This is a very potent drug, the effects can peak rapidly and become uncomfortable and/or overpowering. A psychedelic crisis can occur.


[top]Producing 25B-NBOMe



[top]Forms of 25B-NBOMe

Powder
tabs - Usually 300-350ug
liquid in LSD style dropped bottles


[top]Legal Status of 25B-NBOMe

[top]United Nations

Uncontrolled

[top]USA

Uncontrolled at Federal and State level, though arguably may contravene the Federal Analog Act under certain circumstances given its structural and functional similarity to controlled substance 2C-B.

[top]EU

Legal

[top]United Kingdom

25B-NBOMe is uncontrolled in the United Kingdom, as N-benzyl derivatives of phenethylamine are not covered by the phenethylamine derivatives clause of the Misuse of Drugs Act 1971.

[top]Other Countries



[top]History of 25B-NBOMe


25B-NBOMe was first synthesized by Ralf Heim. [2]


[top]More 25B-NBOMe sections


[top]The Latest 25B-NBOMe Threads

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[top]References

  1. ^ Ettrup, A.; Hansen, M.; Santini, M. A.; Paine, J.; Gillings, N.; Palner, M.; Lehel, S.; Herth, M. M. et al. (2010). "Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers". European Journal of Nuclear Medicine and Molecular Imaging
  2. ^ Ralf Heim PhD. Synthese und Pharmakologie potenter 5-HT2A-Rezeptoragonisten mit N-2-Methoxybenzyl-Partialstruktur. Entwicklung eines neuen Struktur-Wirkungskonzepts. (German)


Contributors: Alfa, Docta, NeuroChi
Created by NeuroChi, 01-06-2011 at 05:48
Last edited by Docta, 15-09-2011 at 06:57
Last comment by Docta on 12-09-2011 at 07:39
1 Comments, 65,147 Views

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