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[top]Introduction to 25I-NBOMe


25I-NBOMe is derived from the psychedelic phenethylamine 2C-I by substitution on the amine with a 2-methoxybenzyl (BOMe) group.

[top]Ways of Administration

Common methods of administration include sublingual and intranasal. The doses are typically volumetrically dosed due to the extremely low dosage for activity (microgram ranges). The dosing method commonly used is liquid or blotter form.

The HCl form is commonly found from RC vendors along with pre-dosed blotters and liquid form already volumetrically dosed using ethanol. Please be aware that blotter form does not assure that the weights specified on the the websites are true, so take care to dose conservatively.

[top]Effects of 25I-NBOMe

Anecdotal reports describe 25I-NBOMe as having a rapid onset when insufflated or taken sublingually. It has been said to be inactive when taken orally, although this is unconfirmed.

[top]Combinations with 25I-NBOMe

[top]Different Uses for 25I-NBOMe

[top]Pharmacology of 25I-NBOMe

25I-NBOMe is a potent partial agonist at the 5-HT2A receptor. [1]

[top]Chemistry of 25I-NBOMe

The following image displays the structural relationship between 2C-I, 2-methoxytoluene, and 25I-NBOMe.

[top]The Dangers of 25I-NBOMe

25I-NBOMe is a novel and potent research chemical. Little is known about it's safety or toxicity. Much like 25C-NBOMe, dosing is usually done volumetrically due to the general unavailability of scales that can accurately measure micrograms.

These are the dangers common to all psychedelic drugs:

Accidental injury.
When on a psychedelic drug, it is easier to accidentally injure yourself. Also because of the disorientating and potentially delusion inspiring nature of the experience, you could be lead to inflict harm on others or yourself. People have fallen off rooftops, run into traffic, attempted to throw people off rooftops as 'sacrifices', drowned, and so on. The best way of protecting against this is to have a friend with you who is sober to look after you and handle any negative situation that might arise.

Bad trips. A bad trip is a negative psychedelic experience. It can range from a mildly negative feeling of anxiety/discomfort, to full-blown psychosis. Bad trips usually ruin a psychedelic experience for the tripper and everyone else. Most bad trips are manageable, just very uncomfortable and difficult. Some are extreme and unmanageable though. It's not uncommon for a bad trip to result in lingering psychological issues. Usually just a few days of negative emotions and anxiety. Sometimes, however, a week or so of serious anxiety, destabilized mental state and impaired functioning is possible. On very rare occasions, a month or two of severely diminished functioning, traumatized mental state, depression & crippling anxiety can occur. More information on bad trips can be found here. The best way of avoiding a bad trip is having the correct set and setting.

Permanent psychosis. Psychedelics are believed by researchers not to cause permanent psychosis, however they could trigger a latent mental illness in someone who was already predisposed to it, or make existing mental illnesses worse. If there is a history of mental illness in your family, you are more likely to be predisposed. Everyone is at some risk, however.

PTSD, anxiety disorder, depression & depersonalization. There are anecdotal reports of the trauma inflicted by some bad trips leading to depression and anxiety which while usually temporary, could potentially develop into lasting disorders. While no different to the potential of any traumatic event to cause lasting disorders, nonetheless this is a danger of psychedelic drug use.

[top]Forms of 25I-NBOMe

[top]Legal Status of 25I-NBOMe

[top]United Nations



Uncontrolled at Federal and State level, though arguably may contravene the Federal Analog Act under certain circumstances given its structural and functional similarity to controlled substance 2C-B.



[top]United Kingdom

25I-NBOMe is uncontrolled in the United Kingdom, as N-benzyl derivatives of phenethylamine are not covered by the phenethylamine derivatives clause of the Misuse of Drugs Act 1971.

[top]Other Countries

[top]History of 25I-NBOMe

[top]The Latest 25I-NBOMe Threads

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Created by NeuroChi, 01-06-2011 at 06:09
Last edited by Joe-(5-HTP), 29-07-2015 at 00:14
Last comment by azinuamid on 11-02-2014 at 15:46
2 Comments, 126,255 Views

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