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[top]Introduction to 4-FA


4-fluoroamphetamine acts as both a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine. Common names: 4-Fluoroamphetamine; 4-FMP; para-fluoroamphetamine; and RDJ.


[top]Using 4-FA

[top]Ways of Administration

The two most common routes of administration for 4-FA are intranasal and oral consumption, with oral consumption being the primary route of administration among researchers, due to the rather painful burning sensation that is accompanied with intranasal administration.

[top]Oral use of 4-FA

[top]Nasal use of 4-FA

[top]Anal use of 4-FA

[top]Smoking 4-FA

[top]Effects of 4-FA

[top]Positive

  • Euphoria
  • Increase in energy (stimulation)
  • Increased awareness of senses
  • Increased appreciation for music
  • Feelings of love and empathy

[top]Neutral

  • Loss of appetite
  • Mild visual hallucinations
  • Restlessness
  • Increased perspiration
  • Changes in body temperature regulation
  • Increased sensitivity to light

[top]Negative

  • Tachycardia
  • Anxiety or paranoia
  • Agitation
  • Clenching of the jaw (bruxism)
  • Difficulty concentrating
  • Insomnia
  • Nausea and vomiting

[top]Combinations with 4-FA

[top]Different Uses for 4-FA



[top]Pharmacology of 4-FA


4-fluoroamphetamine is a release agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine. The respective EC50 values are 2.0 x 10−7 M, 7.3 x 10−7 M, and 3.7 x 10−8 M, while the IC50 values are 7.7 x 10−7 M, 6.8 x 10−6 M, and 4.2 x 10−7 M.[1]

Regarding the metabolic fate of 4-FA, it is likely excreted from the body entirely unchanged. The C-F bond at the 4-position on the phenyl ring likely resists deactivation in the liver by cytochrome P450 oxidase[2]


[top]Chemistry of 4-FA


Systematic (IUPAC) name:(RS)-1-(4-fluorophenyl)propan-2-amine
Synonyms:4-fluoroamphetamine, p-fluoroamphetamine, 4-FA
Molecular Formula:C9H12FN
Molar mass:153.20 g/mol [1]
CAS Registry Number:459-02-9
Melting Point: 
Boiling Point:215.2C @ 760mmHg (to be verified)
Flash Point:93.6 C (to be verified)
Solubility: 
Additionnal data: 
Notes: 


[top]The Dangers of 4-FA



[top]Producing/Growing 4-FA



[top]Forms of 4-FA



[top]Legal Status of 4-FA

[top]United Nations

[top]USA


4-FA is unscheduled in the United States, however it may be considered an analog of PMA, in which case it may be prosecuted under the Federal Analog Act if intent for human consumption is present.

As of 7/1/12, 4-FA is a schedule 1 substance in the state of Virginia.

[top]EU


As of 1/1/2012 4-FA is illegal to possess, buy, or sell in Germany.

Illegal in Finland since 2011.

[top]Other Countries

[top]Israel


4-FA was added to Israel's list of controlled substances in December of 2007, making it illegal to possess, buy, or sell.

[top]Poland


4-FA is a controlled substance in poland.

[top]Slovak Republic


As of March 1, 2011, Spice-type cannabinoid receptor agonists, 4-Fluoroamphetamine, MDBD, bk-MBDB, bk-MDMA, and 4-Methylmethcathinone are to be considered controlled substances in the Slovak Republic.

[top]United Kingdom


4-FA is considered to be a Class A drug under the Misuse of Drugs Act.


[top]Images of 4-FA



[top]History of 4-FA

Popularity of 4-FA over time:



[top]More 4-FA Sections



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[top]References

  1. ^ http://www.unc.edu/~dlinz/Papers/The%20effects%20of%20non-medically%20used%20psychoactive%20drugs%20on%20mon oamine%20neurotransmission%20in%20rat%20brain.pdf
  2. ^ http://www.ncbi.nlm.nih.gov/pubmed/16445122

[1] Calculated from Atomic Weights of the Elements, 2007


Created by User-126494, 14-01-2012 at 04:00
Last edited by John_bob, 06-07-2014 at 11:27
Last comment by Bass_spacecase1 on 08-01-2014 at 03:58
9 Comments, 22,005 Views

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4-fa, 4-fmp, amphetamines, halogenated amphetamines, research chemicals
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