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The Mandelin reagent is one of many drug identification reagents. It changes color in the presence of a compound in a predictable fashion and can be used to help infer the potential identity of a compound.


[top]Introduction to The Mandelin Reagent

Its advantage is that it can test for PMA which has a behavioral profile similar to that of MDMA but is extremely dangerous at the same dose as that of a common MDMA dose. It can also test for ketamine.
Tests for: MDxx, (meth)amphetamine, PMA, and ketamine.

[top]Testing with Mandelin reagent

One can apply a few drops of the Mandelin reagent to a sample of the compound on glass or ceramic. Be careful with test regents, they can be corrosive. Handle in a well ventilated area, gasses can emerge from the reaction.

Observe the color change. Compare with chart below. [1]

[top]Known color changes with Mandelin reagent

Dimethoxy-meth HCl Dark olive brown
Doxepin HCl Dark reddish brown
Dristan powder Grayish olive
Exedrine powder Dark olive
MDA HCl Bluish black
Mescaline HCl Dark yellowish brown
Methadone Dark grayish blue
Methaqualone Very orange yellow
Methylphenidate Brilliant orange yellow
Morphine monohydrate Dark grayish reddish Brown
Opium Dark brown
Oxycodone HCl Dark greenish yellow
Procaine HCl Deep orange
Propoxyphene HCl Dark reddish brown
Quinine HCl Deep greenish yellow
Salt crystals Strong orange

[top]Making Mandelin reagent

Dissolve 1.0 g of ammonium metavanadate in 100 mL of concentrated sulfuric acid. [2]

[top]Danger of the Mandelin reagent

1. Ammonium metavanadate - TOXIC. Toxic by inhalation, in contact with skin, and if swallowed. Irritating to eyes and respiratory system. Risk of serious damage to eyes. Possible risk of irreversible effects. Possiblem utagen. In case of accident or if you feel unwell, seek medical advice immediately. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves, and eye/face protection.[2]

2. Sulfuric acid - OXIDIZER, ACID, TOXIC, CORROSIVE. Liquid and mist cause severe burns to all body tissue. May be fatal if swallowed. Harmful if inhaled.
Inhalation may case lung damage. Do not get liquid in eyes, on skin, or clothing. Wash thoroughly after handling. Avoid breathing vapors. Use with adequate ventilation. Do not add water to contents while in container because of violent reaction. Store in tightly closed container. Wear suitable protective clothing and gloves.[2]

[top]How the Mandelin reagent works

This section needs to be written. Please contact NeuroChi if you would like to help.

[top]Compounds tested with Mandelin reagent

The following is a list of compounds tested by Drugs Forum members with the Mecke reagent.

Verified refers to whether or not the compound was verified by a third party lab (ie. GC/MS results confirm).

Color refers to the best description of the color either by image upload or user(s) description. Please see the thread linked for more information.

Compound Verified? Color Other notes
4-FA [1] no Yellow/orange  
4-FA [2] no Light yellow/green
4-FA [3] no Yellow/green user believes this is 4-FA
4-FMA [1] no Yellow/green user comments this compound is barely active in high doses
6-APB [1] no Dark green user describes this compound as supposedly 6-APB, though very impure
JWH-073 [1] no yellow > green  
JWH-081 [1] no orange  
JWH-250 [1] no bright red  
MDPV [1] no Green then dark orange no rxn to Simons or Robadope, implies tertiary amine (MDPV)
MDPV [2] no Orange* no rxn to Simons or Robadope, implies tertiary amine (MDPV)
Methylone [1] no Yellow
Naphyrone [1] no Yellow then orange rxn to Simons, implies secondary amine (not Naphyrone)


  1. ^ EZ Test Mandelin: The classic test for ecstasy. EZ Test. Located here: http://www.eztest.com/dir2/ez-test-mecke-the-classic-test-for-ecstasy. (Accessed July 29, 2011).
  2. ^ a b c d Reagent A.4. Colour Test Reagents-Kits for Preliminary Identification of Drugs of Abuse. National Institute of Justice.

Attached Images
File Type: jpg ez_mandelin.jpg (23.6 KB, 508 views)
Created by NeuroChi, 29-06-2011 at 17:41
Last comment by NeuroChi on 29-06-2011 at 17:46
1 Comments, 20,043 Views

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