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a-PVP

a-PVP is a powerful synthetic stimulant drug which functions as a norepinephrine-dopamine reuptake inhibitor (NDRI), being roughly a quarter the potency of MDPV the effects are said to be comparable.

Contents




[top]Introduction to a-PVP

a-PVP, α-Pyrrolidinopentiophenone is an alkaloid in the pyrrolidine and ketone chemical classes, functioning as a norepinephrine-dopamine reuptake inhibitor (NDRI) and acting as a stimulant on the central nervous system and cardiovascular system. a-PVP was developed in the 1960 and has been available on the research chemical market for several years now, and is used as a recreational drug.


[top]Using a-PVP

[top]Ways of Administration

a-PVP can be administered orally, sublingually, rectally, intravenously, insufflated, and inhaled with varying doses according to the route of administration. There is a great tendency to redose with this compound which is dependent on the route of administration, care should be taken, as it is suggested not to dose more then once an hour.

[top]Effects of a-PVP

Positive
Euphoria
Stimulation
Concentration (Dose dependent)

Negative
Anxiety
Paranoia
Psychosis
Muscle Tension
Vasoconstriction
Tachycardia

[top]Dosing of a-PVP

Intravenous
Threshold< 2mg
Low2-5mg
Moderate5-10mg
High10-20mg
Very High20-30mg
Insufflation
Threshold1-5mg
Low5-20mg
Moderate20-30mg
High30-40mg
Very High40-60mg
Oral
Threshold1-5mg
Low5-25mg
Moderate25-45mg
High45-70mg
Very High75-100mg
Vaporized
 
Low
Moderate
High
Very high
(Note: vaporization dose is very subjective due to high tendency to frequently redose. This represents one dose only.)


[top]Chemistry of a-PVP


Systematic(IUPAC) name:(RS)-1-phenyl-2-(1-pyrrolidinyl)-1-pentanone
Synonyms:alpha-Pyrrolidinovalerophenone, O-2387, alpha-PVP, 1-Phenyl-2-(pyrrolidin-1-yl)pentan-1-one
Molecular Formula:C15H21NO, C15H21NO.HCl (hydrochloride)
Molar mass:231.33 g/mol, 267.79 g/mol (hydrochloride) [2]
CAS Registry Number:14530-33-7, 5485-65-4 (hydrochloride)
Melting Point:161.3 C
Boiling Point:no data
Flash Point:no data
Solubility (HCl):~10 mg/mL in PBS (pH 7.2), ~20 mg/mL (ethanol), ~10 mg/mL (dimethylsulfoxide), ~3 mg/mL (dimethylformamide) (source ?)
Additionnal data:none
Notes:Hydrochloride aspect : white powder
[1]

MSDS Downloadable .pdf
Attachment 30859


[top]Appearance of a-PVP

A-PVP often comes in either a white, tan, or a yellowish powder, it is also available in very small white crystals. The difference in color is unknown, however the crystals are said to have a different effect then the powder.


[top]Legal Status of a-PVP

[top]United Nations

[top]USA

A-PVP has recently become a Scheduled 1 substance under Federal Law.

[top]EU

[top]Finland

Illegal in Finland since 2013.

[top]Other Countries




[top]References


[1] α-PVP monograph
[2] Calculated from Atomic Weights of the Elements, 2007


Created by syntheticdave, 23-12-2012 at 20:10
Last edited by John_bob, 08-07-2014 at 22:15
Last comment by methylman251 on 02-10-2014 at 02:39
9 Comments, 93,416 Views

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