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boro-meth -unusual racemic meth

courtesy DEA's Microgram UNUSUAL RACEMIC METHAMPHETAMINE SAMPLE IN DETROIT, MICHIGAN (LIKELY PREPARED BY A BOROHYDRIDE REDUCTION METHOD) The Special Testing and Research Laboratory (Dulles, Virginia) recently received an evidence envelope containing a small amount of a pasty, orange colored material, suspected methamphetamine (see Photo 11). The sample was an exemplar from five kilogram-sized bricks seized in Detroit, Michigan, by Customs and Border Protection Officers, incidental to a search of vehicle entering from Canada. Analysis of the material (total net mass approximately 3 grams) by GC/MS and CE indicated a mixture of 78% d,l-methamphetamine hydrochloride and 16% 1-phenyl-2-propanol. Detailed profiling by GC/MS and ICP/MS confirmed the presence of marker impurities corresponding to a reductive amination route, and (unusually) an extremely high boron concentration. The collective results indicate synthesis via a reductive amination of 1-phenyl-2-propanone (phenylacetone, P2P) using sodium borohydride or a similar compound. This is the first such submission to the Special Testing and Research Laboratory. [Editor’s Notes: MDMA is typically prepared by clandestine chemists in Canada via reductive amination of 1-(3',4'-methylenedioxyphenyl)-2-propanone (MDP2P) using sodium borohydride or sodium cyanoborohydride. Previous reports from Canadian law enforcement personnel have indicated that bulk quantities of MDP2P and P2P are occasionally co-smuggled into Canada. It would appear that this sample resulted from an attempted MDMA prep that used the wrong precursor (i.e., P2P). The contaminant 1-phenyl-2-propanol results from reduction of P2P, and the large amount of it (and the boron compounds) in the sample confirms a very poorly executed “cook.” The physiological consequences of abuse of methamphetamine contaminated with excessive 1-phenyl-2-propanol and boron compounds are unknown.]

boro-meth -unusual racemic meth