cheese heroin and tylenol PM
- INTELLIGENCE ALERT - MOROXYDINE HYDROCHLORIDE FOUND IN A HEROIN EXHIBIT FROM LAOS The DEA Special Testing and Research Laboratory (Dulles, Virginia) recently received an off-white granular substance submitted to the laboratory for analysis from the DEA Country Office in Vientiane, Laos, suspected morphine. The substance was seized by Laotian authorities in an undisclosed area of Laos. Analysis of the substance (total net mass 6.8 grams) by GC/MS, CE, and proton-NMR, however, indicated not morphine but rather 23 percent heroin (calculated as the hydrochloride), along with 26 percent caffeine, 7 percent acetaminophen, 7 percent O6-monoacetylmorphine (also calculated as the hydrochloride), and an unknown compound. The unknown was detected by CE and NMR, but not by GC/FID or GC/MS (either directly or following MSTFA derivatization). Further analysis of the chloroform insolubles (containing the unknown) by FTIR, LC/MS/MS, and advanced 1- and 2-dimensional NMR techniques indicated 20 percent moroxydine HCl (see Figure 1), an antiviral medicine. This substance does not appear to be used in the United States, but it is commercially available in many other areas of the world. It is unclear why it would be utilized as a heroin adulterant. This is the first submission of a sample containing this unusual adulterant to the Special Testing and Research Laboratory. - SPECIAL INTELLIGENCE BRIEF - "CHEESE" Officer Jeremy Liebbe &#8232;Forensics and Evidence &#8232;Dallas ISD Police Department &#8232;1402 Seegar &#8232;Dallas, TX 75215 [Taken in Part from the Narcotics Information Bulletin of the Same Title; &#8232;Unclassified; Reprinted with Permission.] Between August 15, 2005, and March 1, 2006, the Dallas Independent School District Police Department handled 54 felony offenses and 24 found property cases involving a new drug mixture known on the street as “Cheese,” a so-called “starter form” of heroin. “Cheese” is typically found folded inside a small paper bindle, and in the Dallas area is popular among Hispanic juveniles, both male and female, with known users as young as 13 years old. It is typically encountered as a light tan colored powder with granules varying from fine powder to 1.5 millimeters in size (see Photo 9). It is administered by insufflating (snorting) the powder into the nose through a tube, much in the same fashion as is practiced with cocaine. Users have described the effects as causing euphoria, disorientation, lethargy, sleepiness, and hunger. As with any form of heroin, “Cheese” appears to be highly addictive, and withdrawal symptoms may onset as fast as within 12 hours of cessation of use. Analysis of “Cheese” samples shows that it contains acetaminophen, diphenhydramine hydrochloride, and up to 8 percent heroin. Due to chemical interference caused by the acetaminophen and diphenhydramine hydrochloride, forensic analysis of “Cheese” can be challenging. It is believed that “Cheese” is manufactured by mixing a small quantity of heroin with a large quantity of crushed Tylenol-PM® caplets (that is, a commonly available formulation of acetaminophen and diphenhydramine hydrochloride).