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Chlorpromazine

Thorazine (chlorpromazine) is 10-(3-dimethylaminopropyl)-2-chlorphenothiazine, a dimethylamine derivative of phenothiazine. It is present in oral and injectable forms as the hydrochloride salt, and in the suppositories as the base. Tablets — Each round, orange, coated tablet contains chlorpromazine hydrochloride as follows: 10 mg imprinted SKF and T73; 25 mg imprinted SKF and T74; 50 mg imprinted SKF and T76; 100 mg imprinted SKF and T77; 200 mg imprinted SKF and T79. Inactive ingredients consist of benzoic acid, croscarmellose sodium, D&C Yellow No. 10, FD&C Blue No. 2, FD&C Yellow No. 6, gelatin, hydroxypropyl methylcellulose, lactose, magnesium stearate, methylparaben, polyethylene glycol, propylparaben, talc, titanium dioxide and trace amounts of other inactive ingredients. Spansule® sustained release capsules — Each Thorazine Spansule® capsule is so prepared that an initial dose is released promptly and the remaining medication is released gradually over a prolonged period. Each capsule, with opaque orange cap and natural body, contains chlorpromazine hydrochloride as follows: 30 mg imprinted SKF and T63; 75 mg imprinted SKF and T64; 150 mg imprinted SKF and T66. Inactive ingredients consist of benzyl alcohol, calcium sulfate, cetylpyridinium chloride, FD&C Yellow No. 6, gelatin, glyceryl distearate, glyceryl monostearate, iron oxide, povidone, silicon dioxide, sodium lauryl sulfate, starch, sucrose, titanium dioxide, wax and trace amounts of other inactive ingredients. Ampuls — Each mL contains, in aqueous solution, chlorpromazine hydrochloride, 25 mg; ascorbic acid, 2 mg; sodium bisulfite, 1 mg; sodium chloride, 6 mg; sodium sulfite, 1 mg. Multi-Dose Vials — Each mL contains, in aqueous solution, chlorpromazine hydrochloride, 25 mg; ascorbic acid, 2 mg; sodium bisulfite, 1 mg; sodium chloride, 1 mg; sodium sulfite, 1 mg; benzyl alcohol, 2%, as a preservative. Syrup — Each 5 mL (1 teaspoonful) of clear, orange-custard flavored liquid contains chlorpromazine hydrochloride, 10 mg. Inactive ingredients consist of citric acid, flavors, sodium benzoate, sodium citrate, sucrose and water. Suppositories — Each suppository contains chlorpromazine, 25 or 100 mg, glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids and hydrogenated palm kernel oil fatty acids.

Chlorpromazine
BA, Nov 27, 2009
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  • Category:
    Antipsychotics
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    BA
    Date:
    Nov 27, 2009
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