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5-HTP efficacy and contraindications

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  1. Scrofula
    Study Author(s):
    Marty Hinz, Alvin Stein, Thomas Uncini3
    Journal Name:
    Neuropsychiatric Disease and Treatment
    Publication Date:
    18 July 2012
    L-5-hydroxytryptophan (5-HTP) is the immediate precursor of serotonin. It is readily synthesized into serotonin without biochemical feedback. This nutrient has a large and strong following who advocate exaggerated and inaccurate claims relating to its effectiveness in the treatment of depression and a number of other serotonin-related diseases. These assertions are not supported by the science. Under close examination, 5-HTP may be contraindicated for depression in some of the very patients for whom promoters of 5-HTP advocate its use. Keywords: 5-HTP, 5-hydroxytryptophan, L-5-HTP, L-5-hydroxytryptophan