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Biosynthesis Of Mescaline In Peyote

Indicates that alternative routes to mescaline are available.

  1. Calliope
    Tetrahedron Letters No.26, Pp. 2433-2435, 1967.


    Stig Agurell, Jan Lundstrom And Finn Sandberg

    The results snow that both tyrosine (I R=Hl) and 3,4-dihydroxyprenylalanine (I R=OH) and the corresponding amines are utilized as precursors of mescaline. Kovacs and ,Jindra (6) have shown that tyrosine may be converted to 3,4-dihydroxyphenylalanine also in plants. The latter compound was particularly effectively incorporated in the present study. The incorporation into mescaline of both tyramine and 3,4-dihydroxypnenylalanine, both presumably products of tyrosine, but on different paths, indicates that alternative routes to mescaline are available.