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Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model

Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model

  1. catseye
    ARTICLE IN PRESS, European Journal of Pharmacology xxx (2012) xxx–xxx

    Alison Ribeiro, Viviane Ferraz-de-Paula, Milena L. Pinheiro, Luana B. Vitoretti, Domenica P. Mariano-Souza, Wanderley M. Quinteiro-Filho, Adriana T. Akamine, Vinícius I. Almeida, João Quevedo, Felipe Dal-Pizzol, Jaime E. Hallak, Antônio W. Zuardi, José A. Crippa, João Palermo-Neto

    ABSTRACT:
    Acute lung injury is an inflammatory condition for which treatment is mainly supportive because effective therapies have not been developed. Cannabidiol, a non-psychotropic cannabinoid component of marijuana (Cannabis sativa), has potent immunosuppressive and anti-inflammatory properties. Therefore, we investigated the possible anti-inflammatory effect of cannabidiol in a murine model of acute lung injury.