1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP

Cannabimimetic Activity in Rats and Pigeons of HU 210, a Potent Antiemetic Drug

Cannabimimetic Activity in Rats and Pigeons of HU 210, a Potent Antiemetic Drug

  1. helikophis
    FERRARI, F., A. OTTANI ANDD. GIULIANI.
    Cannabimimetic activity in rats and pigeons of HU 210, a potent anti- emetic drug. PHARMACOL BIOCHEM BEHAV 62 (1) 75–80, 1999.—Preliminary behavioral experiments in rats with the cannabinoid agonist HU 210 (12.5–100 g/kg IP) showed that it has a potent cannabimimetic profile similar to that of d-9 THC; the drug dose dependently depressed locomotor activity, rearing, and grooming and elicited vocalization and circling at the highest doses. In subsequent studies on pigeons, HU 210 (12.5–50 g/kg SC) confirmed its sedative effects; it also afforded protection against vomiting induced by cisplatin (7.5 mg/kg IV) and emetine (20 mg/kg SC) and emetine-induced head shake.