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Cannabis for migraine treatment: the once and future prescription? An historical and scientific revi

Cannabis for migraine treatment: the once and future prescription? An historical and scientific revi

  1. Behrang
    Pain. 1998 May;76(1-2):3-8

    Ethan Russo

    Abstract:
    Cannabis, or Marijuana, has been used for centuries for both symptomatic and prophylactic treatment of migraine. It was highly esteemed as a headache remedy by the most prominent physicians of the age between 1874 and 1942, remaining part of the Western pharmacopoeia for this indication even into the mid-twentieth century. Current ethnobotanical and anecdotal references continue to refer to its efficacy for this malady, while biochemical studies of THC and anandamide have provided a scientific basis for such treatment. The author believes that controlled clinical trials of Cannabis in acute migraine treatment are warranted.

    Keywords:
    Migraine, Headache, Cannabis, Marijuana, Dronabinol, Ethnobotany

    http://www.ncbi.nlm.nih.gov/pubmed/9696453
    https://www.maps.org/mmj/russo_98_migraine_pain.pdf