1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP

Cardiotoxicity Associated with Methamphetamine Use and Signs of Cardiovascular Pathology Among Metha

Cardiotoxicity Associated with Methamphetamine Use and Signs of Cardiovascular Pathology Among Metha

  1. BitterSweet
    Sharlene Kaye and Rebecca McKetin; Cardiotoxicity Associated with Methamphetamine Use and Signs of Cardiovascular Pathology Among Methamphetamine Users
    Technical Report No. 238
    ISBN: 0 7334 2312 4 ©NDARC 2005

    Methamphetamine increases catecholamine activity in the branch of the peripheral nervous system responsible for modulating heart rate and blood pressure. Excessive catecholamine activity is thought to be the primary mechanism underlying the cardiotoxic effects of methamphetamine. High catecholamine levels are known to be cardiotoxic, causing narrowing and spasm of the blood vessels, rapid heart rate (tachycardia), high blood pressure (hypertension), and possible death of the heart muscle. Other features of catecholamine toxicity include the formation of fibrous tissue and an increase in the size of heart muscle cells.