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Changes in brain striatum dopamine and acetylcholine receptors induced by chronic CDP-choline treatm

Changes in brain striatum dopamine and acetylcholine receptors induced by chronic CDP-choline treatm

  1. NeuroChi
    Treated animals displayed an increase in the dopamine receptor densities of 11% for those receiving
    l00mgkg-I and 18% for those receiving 500mgkg- as compared to the control aged animals that had
    received no CDP-choline. Control animals showed, from 2 months to 19 months of life, a 28% decrease in
    the receptor density. No change in the affinity of the receptors for spiroperidol was found in the treated or
    untreated animals.