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Comparison of the Effects of Antidepressants and Their Metabolites on Reuptake of Biogenic Amines an

Comparison of the Effects of Antidepressants and Their Metabolites on Reuptake of Biogenic Amines an

  1. Bajeda
    Sánchez C, Hyttel J. Cell Mol Neurobiol. 1999 Aug;19(4):467-89.

    The present survey compares the effects of antidepressants and their principal metabolites on reuptake of biogenic amines and on receptor binding. The following antide-pressants were included in the study: the tricyclic antidepressants amitriptyline, dothiepin, and lofepramine and the atypical antidepressant bupropion, which all have considerable market shares in the UK and/or US markets; the selective serotonin reuptake inhibitors (SSRIs) citalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline; and the recently approved antidepressants venlafaxine and nefazodone.