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CYTOCHROME P450 DRUG INTERACTION TABLE

CYTOCHROME P450 DRUG INTERACTION TABLE

  1. Rob Cypher
    This table is designed as a hypothesis testing, teaching and reference tool for physicians and researchers interested in drug interactions that are the result of competition for, or effects on the human cytochrome P450 system.

    The table contains lists of drugs in columns under the designation of specific cytochrome P450 isoforms. A drug appears in a column if there is published evidence that it is metabolized, at least in part, via that isoform. It does not necessarily follow that the isoform is the principal metabolic pathway in vivo, or that alterations in the rate of the metabolic reaction catalyzed by that isoform will have large effects on the pharmacokinetics of the drug.

    Flockhart DA. Drug Interactions: Cytochrome P450 Drug Interaction Table. Indiana University School of Medicine (2007). http://medicine.iupui.edu/clinpharm/ddis/table.aspx

Recent Reviews

  1. Rob Cypher
    Rob Cypher
    5/5,
    Version: 2013-03-22
    This one is more recent compared to the other chart in the documents (2007 vs. 1999).