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Effects of Psilocybe argentipes on marble-burying behavior in mice (2009)

Effects of Psilocybe argentipes on marble-burying behavior in mice (2009)

  1. Jatelka
    Biosci Biotechnol Biochem. 2009 Aug;73(8):1866-8

    Matsushima Y, Shirota O, Kikura-Hanajiri R, Goda Y, Eguchi F

    Psilocybe argentipes is a hallucinogenic mushroom. The present study examined the effects of P. argentipes on marble-burying behavior, which is considered an animal model of obsessive-compulsive disorder. P. argentipes significantly inhibited marble-burying behavior without affecting locomotor activity as compared with the same dose of authentic psilocybin. These findings suggest that P. argentipes would be efficient in clinical obsessive-compulsive disorder therapy.