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Effects of Psilocybin on Healthy Volunteers

Effects of Psilocybin on Healthy Volunteers

  1. ZenobiaSky
    MAPS-Sponsored Research
    Effects of Psilocybin on Healthy Volunteers
    Investigators: Roland Griffiths PhD, William Richards PhD, Una McCann MD, Robert Jesse
    Sponsor: NIDA, Council for Spiritual Practices, Heffter Research Institute
    Contact: Roland Griffiths, PhD

    A series of studies is planned to investigate the effects of psilocybin in healthy volunteers. The first was a double-blind study evaluating the psychological effects of psilocybin relative to methylphenidate administered under comfortable, supportive conditions. After psilocybin, 61% of subjects met pre-established criteria, for a full mystical experience, and 31% reported significant fears during their psilocybin session. Two months after sessions, 71% of subjects rated their psilocybin experience as among the five most "spiritually significant" experiences of their lifetimes. 79% rated that it had increased their current sense of personal wellbeing or life satisfaction. Fourteen month follow-up data is being analyzed.

    Continuing support for this research program is uncertain and the investigators are attempting to network with individuals or foundations that could help provide support.

    August, 2006