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Evidence for active immunity to morphine in mice (1972)

Evidence for active immunity to morphine in mice (1972)

  1. Calliope
    Science (New York, N.Y.), 1972, Vol.178 (67), pp.1290

    Berkowitz, B ; Spector, S

    Abstract
    The serum from mice actively immunized with a morphine immunogen contained antibodies that could bind dihydromorphine. Morphine effects diminished in these "immunized" mice, and the concentration of morphine plasma was altered.