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Ibogaine interferes with the establishment of amphetamine place preference learning.

Ibogaine interferes with the establishment of amphetamine place preference learning.

  1. ThirdEyeFloond
    Exp Clin Psychopharmacol. 1997 May;5(2):119-22.
    Moroz I, Parker LA, Siegel S.

    The ability of ibogaine, injected 24 hr before amphetamine, to modify the establishment of amphetamine-induced place preference learning was assessed. A single injection of ibogaine blocked the establishment of amphetamine place preference after 1 or 2 conditioning trials, but it was less effective after 4 trials. The reduced effectiveness of ibogaine across multiple conditioning trials appears to be the result of the development of tolerance to ibogaine.